1ZT5

C-terminal domain of Insulin-like Growth Factor Binding Protein-1 isolated from human amniotic fluid complexed with Iron(II)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005520	molecular_function	insulin-like growth factor binding
A	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE2 A 300

Chain	Residue
A	HIS213

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DIO A 400

Chain	Residue
A	LEU180
A	TYR181

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Functional Information from PROSITE/UniProt

site_id	PS00484
Number of Residues	35
Details	THYROGLOBULIN_1_1 Thyroglobulin type-1 repeat signature. YlpnCnkn.GfYhsrQcetsmdgeaglcWCVypwnG

Chain	Residue	Details
A	TYR202-GLY236

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	78
Details	Domain: {"description":"Thyroglobulin type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00500","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Motif: {"description":"Cell attachment site","evidences":[{"source":"PubMed","id":"7504269","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by FAM20C","evidences":[{"source":"PubMed","id":"26091039","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by FAM20C","evidences":[{"source":"PubMed","id":"19765076","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26091039","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7678248","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by FAM20C","evidences":[{"source":"PubMed","id":"26091039","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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