1ZR3
Crystal structure of the macro-domain of human core histone variant macroH2A1.1 (form B)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MES A 500 |
| Chain | Residue |
| A | PRO215 |
| A | ASN316 |
| A | HOH502 |
| A | HOH512 |
| A | HOH583 |
| A | THR216 |
| A | ASN217 |
| A | TYR221 |
| A | GLY223 |
| A | SER275 |
| A | GLY312 |
| A | GLY314 |
| A | ARG315 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:A0A0D2UG83 |
| Chain | Residue | Details |
| A | ASP203 | |
| B | ILE204 | |
| B | VAL226 | |
| B | SER275 | |
| B | GLY312 | |
| B | SER313 | |
| B | GLY314 | |
| B | ASN316 | |
| C | ASP203 | |
| C | ILE204 | |
| C | VAL226 | |
| A | ILE204 | |
| C | SER275 | |
| C | GLY312 | |
| C | SER313 | |
| C | GLY314 | |
| C | ASN316 | |
| D | ASP203 | |
| D | ILE204 | |
| D | VAL226 | |
| D | SER275 | |
| D | GLY312 | |
| A | VAL226 | |
| D | SER313 | |
| D | GLY314 | |
| D | ASN316 | |
| A | SER275 | |
| A | GLY312 | |
| A | SER313 | |
| A | GLY314 | |
| A | ASN316 | |
| B | ASP203 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER170 | |
| B | SER170 | |
| C | SER170 | |
| D | SER170 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER173 | |
| B | SER173 | |
| C | SER173 | |
| D | SER173 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR178 | |
| B | THR178 | |
| C | THR178 | |
| D | THR178 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS167 | |
| C | LYS189 | |
| C | LYS320 | |
| D | LYS167 | |
| D | LYS189 | |
| D | LYS320 | |
| A | LYS189 | |
| A | LYS320 | |
| B | LYS167 | |
| B | LYS189 | |
| B | LYS320 | |
| C | LYS167 |
