1ZL3

Coupling of active site motions and RNA binding

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0005829	cellular_component	cytosol
A	0006396	biological_process	RNA processing
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity
A	0016853	molecular_function	isomerase activity
A	0031119	biological_process	tRNA pseudouridine synthesis
A	0061818	biological_process	tRNA folding
A	0106029	molecular_function	tRNA pseudouridine synthase activity
A	0140098	molecular_function	catalytic activity, acting on RNA
A	0160148	molecular_function	tRNA pseudouridine(55) synthase activity
A	1990481	biological_process	mRNA pseudouridine synthesis

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 901

Chain	Residue
A	LYS31
A	ARG34
A	ARG220
A	SO4902

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 902

Chain	Residue
A	MET23
A	LYS31
A	LEU216
A	ARG220
A	SO4901

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 903

Chain	Residue
A	THR272
A	SER273

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Region: {"description":"RNA binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01080","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11779468","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01080","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11779468","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1ze1

Chain	Residue	Details
A	ASN48
A	TYR76

---