1ZHX
Structure of yeast oxysterol binding protein Osh4 in complex with 25-hydroxycholesterol
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000139 | cellular_component | Golgi membrane |
A | 0005546 | molecular_function | phosphatidylinositol-4,5-bisphosphate binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005794 | cellular_component | Golgi apparatus |
A | 0005829 | cellular_component | cytosol |
A | 0006665 | biological_process | sphingolipid metabolic process |
A | 0006869 | biological_process | lipid transport |
A | 0006887 | biological_process | exocytosis |
A | 0006892 | biological_process | post-Golgi vesicle-mediated transport |
A | 0006897 | biological_process | endocytosis |
A | 0008142 | molecular_function | oxysterol binding |
A | 0008289 | molecular_function | lipid binding |
A | 0015248 | molecular_function | obsolete sterol transporter activity |
A | 0015918 | biological_process | sterol transport |
A | 0016020 | cellular_component | membrane |
A | 0030011 | biological_process | maintenance of cell polarity |
A | 0034727 | biological_process | piecemeal microautophagy of the nucleus |
A | 0035621 | biological_process | ER to Golgi ceramide transport |
A | 0070273 | molecular_function | phosphatidylinositol-4-phosphate binding |
A | 0070300 | molecular_function | phosphatidic acid binding |
A | 0120015 | molecular_function | sterol transfer activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE HC3 A 1001 |
Chain | Residue |
A | PHE13 |
A | HOH1003 |
A | HOH1013 |
A | HOH1266 |
A | LEU24 |
A | GLN96 |
A | TYR97 |
A | ARG100 |
A | GLU107 |
A | LYS109 |
A | ASN165 |
A | GLN181 |
Functional Information from PROSITE/UniProt
site_id | PS01013 |
Number of Residues | 11 |
Details | OSBP Oxysterol-binding protein family signature. EQvSHHPPv.TA |
Chain | Residue | Details |
A | GLU139-ALA149 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22162133, ECO:0007744|PDB:3SPW |
Chain | Residue | Details |
A | LEU24 | |
A | LYS109 | |
A | HIS143 | |
A | LYS336 | |
A | GLU340 | |
A | ARG344 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0007744|PDB:1ZHZ |
Chain | Residue | Details |
A | GLN96 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0007744|PDB:1ZHT |
Chain | Residue | Details |
A | ARG100 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198 |
Chain | Residue | Details |
A | THR370 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
Chain | Residue | Details |
A | SER389 |