1ZGL
Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006955 | biological_process | immune response |
A | 0016020 | cellular_component | membrane |
A | 0019882 | biological_process | antigen processing and presentation |
A | 0042613 | cellular_component | MHC class II protein complex |
B | 0006955 | biological_process | immune response |
B | 0016020 | cellular_component | membrane |
B | 0019882 | biological_process | antigen processing and presentation |
B | 0042613 | cellular_component | MHC class II protein complex |
D | 0006955 | biological_process | immune response |
D | 0016020 | cellular_component | membrane |
D | 0019882 | biological_process | antigen processing and presentation |
D | 0042613 | cellular_component | MHC class II protein complex |
E | 0006955 | biological_process | immune response |
E | 0016020 | cellular_component | membrane |
E | 0019882 | biological_process | antigen processing and presentation |
E | 0042613 | cellular_component | MHC class II protein complex |
G | 0006955 | biological_process | immune response |
G | 0016020 | cellular_component | membrane |
G | 0019882 | biological_process | antigen processing and presentation |
G | 0042613 | cellular_component | MHC class II protein complex |
H | 0006955 | biological_process | immune response |
H | 0016020 | cellular_component | membrane |
H | 0019882 | biological_process | antigen processing and presentation |
H | 0042613 | cellular_component | MHC class II protein complex |
J | 0006955 | biological_process | immune response |
J | 0016020 | cellular_component | membrane |
J | 0019882 | biological_process | antigen processing and presentation |
J | 0042613 | cellular_component | MHC class II protein complex |
K | 0006955 | biological_process | immune response |
K | 0016020 | cellular_component | membrane |
K | 0019882 | biological_process | antigen processing and presentation |
K | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH |
Chain | Residue | Details |
A | TYR161-HIS167 | |
B | TYR171-HIS177 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
Chain | Residue | Details |
P | ASN187 | |
R | ASN187 | |
T | ASN187 | |
V | ASN187 | |
S | ASN149 | |
S | ASN183 | |
U | ASN149 | |
U | ASN183 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
Chain | Residue | Details |
M | ASN194 | |
Q | ASN194 | |
S | ASN194 | |
U | ASN194 | |
G | GLY49 | |
G | ALA52 | |
J | GLY49 | |
J | ALA52 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | MOD_RES: Citrulline => ECO:0000269|PubMed:23828821 |
Chain | Residue | Details |
C | ARG11 | |
F | ARG11 | |
I | ARG11 | |
L | ARG11 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P02687 |
Chain | Residue | Details |
C | THR12 | |
F | THR12 | |
I | THR12 | |
L | THR12 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | GLU55 | |
D | GLU55 | |
G | GLU55 | |
J | GLU55 |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN62 | |
D | ASN62 | |
G | ASN62 | |
J | ASN62 |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ASN69 | |
D | ASN69 | |
G | ASN69 | |
J | ASN69 |
site_id | SWS_FT_FI8 |
Number of Residues | 4 |
Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
Chain | Residue | Details |
A | ARG76 | |
D | ARG76 | |
G | ARG76 | |
J | ARG76 |
site_id | SWS_FT_FI9 |
Number of Residues | 8 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
Chain | Residue | Details |
A | ASN78 | |
A | ASN118 | |
D | ASN78 | |
D | ASN118 | |
G | ASN78 | |
G | ASN118 | |
J | ASN78 | |
J | ASN118 |