1ZCL

prl-1 c104s mutant in complex with sulfate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005769	cellular_component	early endosome
A	0005783	cellular_component	endoplasmic reticulum
A	0005819	cellular_component	spindle
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0006338	biological_process	chromatin remodeling
A	0006470	biological_process	protein dephosphorylation
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0016311	biological_process	dephosphorylation
A	0030335	biological_process	positive regulation of cell migration
A	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
A	0140793	molecular_function	histone H2AXY142 phosphatase activity
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005768	cellular_component	endosome
B	0005769	cellular_component	early endosome
B	0005783	cellular_component	endoplasmic reticulum
B	0005819	cellular_component	spindle
B	0005856	cellular_component	cytoskeleton
B	0005886	cellular_component	plasma membrane
B	0006338	biological_process	chromatin remodeling
B	0006470	biological_process	protein dephosphorylation
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0016311	biological_process	dephosphorylation
B	0030335	biological_process	positive regulation of cell migration
B	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
B	0140793	molecular_function	histone H2AXY142 phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 4397

Chain	Residue
B	ASP72
B	SER104
B	VAL105
B	ALA106
B	GLY107
B	GLY109
B	ARG110

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 4398

Chain	Residue
A	VAL105
A	ALA106
A	GLY107
A	LEU108
A	GLY109
A	ARG110
A	ASP72
A	SER104

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	ASP72
B	ASP72

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160

Chain	Residue	Details
A	SER104
B	SER104

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	VAL105
A	ARG110
B	VAL105
B	ARG110

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1d5r

Chain	Residue	Details
A	SER104
A	ARG110
A	ASP72

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site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1d5r

Chain	Residue	Details
B	SER104
B	ARG110
B	ASP72

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