1ZCL
prl-1 c104s mutant in complex with sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005769 | cellular_component | early endosome |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005819 | cellular_component | spindle |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| A | 0016311 | biological_process | dephosphorylation |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030335 | biological_process | positive regulation of cell migration |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005769 | cellular_component | early endosome |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005819 | cellular_component | spindle |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| B | 0016311 | biological_process | dephosphorylation |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030335 | biological_process | positive regulation of cell migration |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 4397 |
| Chain | Residue |
| B | ASP72 |
| B | SER104 |
| B | VAL105 |
| B | ALA106 |
| B | GLY107 |
| B | GLY109 |
| B | ARG110 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4398 |
| Chain | Residue |
| A | VAL105 |
| A | ALA106 |
| A | GLY107 |
| A | LEU108 |
| A | GLY109 |
| A | ARG110 |
| A | ASP72 |
| A | SER104 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 70 |
| Details | Region: {"description":"Interaction with ATF5","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1d5r |
| Chain | Residue | Details |
| A | SER104 | |
| A | ARG110 | |
| A | ASP72 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1d5r |
| Chain | Residue | Details |
| B | SER104 | |
| B | ARG110 | |
| B | ASP72 |
