Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAD A 1001 |
| Chain | Residue |
| A | GLY16 |
| A | ASN99 |
| A | ALA100 |
| A | GLY101 |
| A | ILE102 |
| A | HIS123 |
| A | THR149 |
| A | SER150 |
| A | SER151 |
| A | TYR164 |
| A | LYS168 |
| A | ALA19 |
| A | PRO194 |
| A | ASN195 |
| A | ALA196 |
| A | SER198 |
| A | ARG199 |
| A | MET200 |
| A | HOH1002 |
| A | HOH1011 |
| A | HOH1012 |
| A | GLY20 |
| A | LEU21 |
| A | ASN39 |
| A | ASP40 |
| A | LEU41 |
| A | SER75 |
| A | VAL76 |
| site_id | AC2 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD B 1002 |
| Chain | Residue |
| B | GLY16 |
| B | ALA19 |
| B | GLY20 |
| B | LEU21 |
| B | ASN39 |
| B | ASP40 |
| B | LEU41 |
| B | SER75 |
| B | VAL76 |
| B | ASN99 |
| B | ALA100 |
| B | GLY101 |
| B | ILE102 |
| B | VAL122 |
| B | HIS123 |
| B | THR149 |
| B | SER150 |
| B | SER151 |
| B | TYR164 |
| B | LYS168 |
| B | PRO194 |
| B | ASN195 |
| B | ALA196 |
| B | SER198 |
| B | ARG199 |
| B | MET200 |
| B | THR201 |
| B | HOH1003 |
| B | HOH1004 |
| B | HOH1024 |
| B | HOH1031 |
| B | HOH1039 |
| B | HOH1056 |
| site_id | AC3 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD C 1003 |
| Chain | Residue |
| C | GLY16 |
| C | ALA19 |
| C | GLY20 |
| C | LEU21 |
| C | ASN39 |
| C | ASP40 |
| C | LEU41 |
| C | GLY43 |
| C | SER75 |
| C | VAL76 |
| C | ASN99 |
| C | ALA100 |
| C | GLY101 |
| C | HIS123 |
| C | THR149 |
| C | SER150 |
| C | SER151 |
| C | TYR164 |
| C | LYS168 |
| C | PRO194 |
| C | ASN195 |
| C | ALA196 |
| C | SER198 |
| C | ARG199 |
| C | MET200 |
| C | HOH1006 |
| C | HOH1007 |
| C | HOH1015 |
| C | HOH1026 |
| C | HOH1047 |
| site_id | AC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAD D 1004 |
| Chain | Residue |
| D | VAL76 |
| D | ASN99 |
| D | ALA100 |
| D | GLY101 |
| D | ILE102 |
| D | HIS123 |
| D | THR149 |
| D | SER150 |
| D | SER151 |
| D | TYR164 |
| D | LYS168 |
| D | PRO194 |
| D | ASN195 |
| D | ALA196 |
| D | SER198 |
| D | ARG199 |
| D | MET200 |
| D | THR201 |
| D | HOH1006 |
| D | HOH1011 |
| D | HOH1025 |
| D | GLY16 |
| D | ALA19 |
| D | GLY20 |
| D | LEU21 |
| D | ASN39 |
| D | ASP40 |
| D | LEU41 |
| D | SER75 |
| site_id | AC5 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD E 1005 |
| Chain | Residue |
| E | GLY16 |
| E | ALA19 |
| E | GLY20 |
| E | LEU21 |
| E | ASN39 |
| E | ASP40 |
| E | LEU41 |
| E | SER75 |
| E | VAL76 |
| E | ASN99 |
| E | ALA100 |
| E | GLY101 |
| E | HIS123 |
| E | THR149 |
| E | SER150 |
| E | SER151 |
| E | TYR164 |
| E | LYS168 |
| E | PRO194 |
| E | ASN195 |
| E | ALA196 |
| E | SER198 |
| E | ARG199 |
| E | MET200 |
| E | THR201 |
| E | HOH1006 |
| E | HOH1017 |
| site_id | AC6 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAD F 1006 |
| Chain | Residue |
| F | GLY16 |
| F | ALA19 |
| F | GLY20 |
| F | LEU21 |
| F | ASN39 |
| F | ASP40 |
| F | LEU41 |
| F | SER75 |
| F | VAL76 |
| F | ASN99 |
| F | ALA100 |
| F | GLY101 |
| F | HIS123 |
| F | THR149 |
| F | SER150 |
| F | SER151 |
| F | TYR164 |
| F | LYS168 |
| F | PRO194 |
| F | ASN195 |
| F | ALA196 |
| F | SER198 |
| F | ARG199 |
| F | MET200 |
| F | THR201 |
| F | HOH1007 |
| F | HOH1012 |
| F | HOH1026 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SasgiygnfgQanYSAAKLGLlGLAnSLA |
| Chain | Residue | Details |
| A | SER151-ALA179 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10001","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 150 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 66 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P51660","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 24 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P51660","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR164 | |
| A | SER151 | |
| A | LYS168 | |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| E | GLN161 | |
| E | LYS168 | |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| F | GLN161 | |
| F | LYS168 | |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR164 | |
| A | LYS168 | |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | TYR164 | |
| B | LYS168 | |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | TYR164 | |
| C | LYS168 | |
| site_id | CSA15 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | TYR164 | |
| D | LYS168 | |
| site_id | CSA16 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| E | TYR164 | |
| E | LYS168 | |
| site_id | CSA17 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| F | TYR164 | |
| F | LYS168 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | TYR164 | |
| B | SER151 | |
| B | LYS168 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | TYR164 | |
| C | SER151 | |
| C | LYS168 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | TYR164 | |
| D | SER151 | |
| D | LYS168 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| E | TYR164 | |
| E | SER151 | |
| E | LYS168 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | GLN161 | |
| A | LYS168 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | GLN161 | |
| B | LYS168 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | GLN161 | |
| C | LYS168 | |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | GLN161 | |
| D | LYS168 | |
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 461 |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 461 |
| site_id | MCSA3 |
| Number of Residues | |
| Details | M-CSA 461 |
| site_id | MCSA4 |
| Number of Residues | |
| Details | M-CSA 461 |
| site_id | MCSA5 |
| Number of Residues | |
| Details | M-CSA 461 |
| site_id | MCSA6 |
| Number of Residues | |
| Details | M-CSA 461 |
