1ZB7

Crystal Structure of Botulinum Neurotoxin Type G Light Chain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 500

Chain	Residue
A	HIS230
A	HIS234
A	GLU268
A	FLC501
A	HOH671

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC A 501

Chain	Residue
A	HIS234
A	GLU268
A	TYR372
A	ZN500
A	HOH682
A	HOH696
A	PHE171
A	THR172
A	HIS230
A	GLU231

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Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TLMHELIHVL

Chain	Residue	Details
A	THR227-LEU236

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	GLU231

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095, ECO:0000269|PubMed:16008342, ECO:0007744|PDB:1ZB7

Chain	Residue	Details
A	HIS230
A	HIS234

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16008342, ECO:0007744|PDB:1ZB7

Chain	Residue	Details
A	GLU268

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