1Z7L

Crystal structure of fragment of mouse ubiquitin-activating enzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
B	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
C	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TBR A 999

Chain	Residue
A	GLN646
A	ARG649
A	ASP650

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TBR B 1000

Chain	Residue
B	GLN646
B	ARG649
B	ASP650

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TBR C 1001

Chain	Residue
C	GLU653
C	GLN646
C	ARG649
C	ASP650

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Functional Information from PROSITE/UniProt

site_id	PS00865
Number of Residues	9
Details	UBIQUITIN_ACTIVAT_2 Ubiquitin-activating enzyme active site. PICTLKnFP

Chain	Residue	Details
A	PRO630-PRO638

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU10132

Chain	Residue	Details
A	CYS632
B	CYS632
C	CYS632

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS671
B	LYS671
C	LYS671

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P22314

Chain	Residue	Details
A	THR800
B	THR800
C	THR800

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site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
A	SER810
A	SER835
B	SER810
B	SER835
C	SER810
C	SER835

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site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079

Chain	Residue	Details
A	SER816
A	SER820
B	SER816
B	SER820
C	SER816
C	SER820

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