1Z3H
The exportin Cse1 in its cargo-free, cytoplasmic state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005049 | molecular_function | nuclear export signal receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006606 | biological_process | protein import into nucleus |
| A | 0006611 | biological_process | protein export from nucleus |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0015031 | biological_process | protein transport |
| A | 0031267 | molecular_function | small GTPase binding |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0046827 | biological_process | positive regulation of protein export from nucleus |
| A | 0051170 | biological_process | import into nucleus |
| A | 0051301 | biological_process | cell division |
| A | 0061015 | biological_process | snRNA import into nucleus |
| B | 0005049 | molecular_function | nuclear export signal receptor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005635 | cellular_component | nuclear envelope |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006606 | biological_process | protein import into nucleus |
| B | 0006611 | biological_process | protein export from nucleus |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0015031 | biological_process | protein transport |
| B | 0031267 | molecular_function | small GTPase binding |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0046827 | biological_process | positive regulation of protein export from nucleus |
| B | 0051170 | biological_process | import into nucleus |
| B | 0051301 | biological_process | cell division |
| B | 0061015 | biological_process | snRNA import into nucleus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 969 |
| Chain | Residue |
| A | ASP796 |
| A | HIS800 |
| B | ASP796 |
| B | HIS800 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 146 |
| Details | Domain: {"description":"Importin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00115","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"HEAT 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"HEAT 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 72 |
| Details | Repeat: {"description":"HEAT 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 62 |
| Details | Repeat: {"description":"HEAT 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 114 |
| Details | Repeat: {"description":"HEAT 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 88 |
| Details | Repeat: {"description":"HEAT 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 136 |
| Details | Repeat: {"description":"HEAT 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 104 |
| Details | Repeat: {"description":"HEAT 9"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 86 |
| Details | Repeat: {"description":"HEAT 10"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"HEAT 11"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 86 |
| Details | Repeat: {"description":"HEAT 13"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 43 |
| Details | Repeat: {"description":"HEAT 14"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"HEAT 15"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 68 |
| Details | Repeat: {"description":"HEAT 16"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"HEAT 17"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 62 |
| Details | Repeat: {"description":"HEAT 18"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 30 |
| Details | Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
