1Z3E
Crystal Structure of Spx in Complex with the C-terminal Domain of the RNA Polymerase Alpha Subunit
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003899 | molecular_function | DNA-directed 5'-3' RNA polymerase activity |
| B | 0006351 | biological_process | DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | HIS0 |
| A | HOH449 |
| A | MET1 |
| A | VAL63 |
| A | GLU85 |
| A | HIS86 |
| A | ASP97 |
| A | GLU98 |
| A | HOH409 |
| A | HOH410 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | CYS10 |
| A | THR11 |
| A | SER12 |
| A | ARG92 |
| A | SO4403 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | SER58 |
| A | ARG91 |
| A | ARG92 |
| A | SO4401 |
| A | HOH442 |
| A | HOH471 |
| A | HOH473 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 402 |
| Chain | Residue |
| B | HOH131 |
| B | LYS245 |
| B | LEU249 |
| B | GLY292 |
| B | ARG293 |
| B | LYS294 |
