1Z2O

Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with mg2+/ADP/Ins(1,3,4,6)P4

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0000166	molecular_function	nucleotide binding
X	0000287	molecular_function	magnesium ion binding
X	0005524	molecular_function	ATP binding
X	0016301	molecular_function	kinase activity
X	0016740	molecular_function	transferase activity
X	0016853	molecular_function	isomerase activity
X	0032957	biological_process	inositol trisphosphate metabolic process
X	0046872	molecular_function	metal ion binding
X	0047325	molecular_function	inositol-3,4,5,6-tetrakisphosphate 1-kinase activity
X	0052725	molecular_function	inositol-1,3,4-trisphosphate 6-kinase activity
X	0052726	molecular_function	inositol-1,3,4-trisphosphate 5-kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG X 1295

Chain	Residue
X	ASP275
X	ASP289
X	ADP871
X	I4P2699
X	HOH2700

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG X 1296

Chain	Residue
X	HOH2703
X	ASP289
X	ASN291
X	ADP871
X	HOH2702

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site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE ADP X 871

Chain	Residue
X	ARG94
X	PRO109
X	LYS136
X	HIS147
X	MET149
X	GLN168
X	HIS169
X	TYR170
X	ILE171
X	HIS173
X	ILE177
X	SER194
X	LEU195
X	ASN210
X	ASP275
X	VAL288
X	ASP289
X	MG1295
X	MG1296
X	I4P2699
X	HOH2700
X	HOH2702
X	HOH2703
X	HOH2714
X	HOH2770
X	HOH2919
X	HOH3186
X	HOH3205

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site_id	AC4
Number of Residues	33
Details	BINDING SITE FOR RESIDUE I4P X 2699

Chain	Residue
X	LYS17
X	THR20
X	LYS57
X	GLN141
X	GLY142
X	HIS147
X	LYS179
X	PHE181
X	ASP275
X	ASP289
X	ASN291
X	PRO294
X	SER295
X	TYR296
X	ADP871
X	MG1295
X	HOH2700
X	HOH2702
X	HOH2715
X	HOH2781
X	HOH2840
X	HOH2856
X	HOH2919
X	HOH2922
X	HOH2927
X	HOH2930
X	HOH2980
X	HOH3044
X	HOH3074
X	HOH3119
X	HOH3165
X	HOH3172
X	HOH3201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z2P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z2O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1Z2P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z2N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z2N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z2P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15837423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z2P","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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