1Z26
Structure of Pyrococcus furiosus Argonaute with bound tungstate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0044355 | biological_process | clearance of foreign intracellular DNA |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE WO4 A 771 |
| Chain | Residue |
| A | GLU329 |
| A | LYS668 |
| A | HIS682 |
| A | LYS683 |
| A | WO4772 |
| A | HOH848 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE WO4 A 772 |
| Chain | Residue |
| A | WO4771 |
| A | GLN326 |
| A | GLU329 |
| A | LYS668 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE WO4 A 773 |
| Chain | Residue |
| A | ASN8 |
| A | ILE143 |
| A | HIS144 |
| A | ILE145 |
| A | ARG296 |
| A | LEU300 |
| A | ARG662 |
| A | PHE664 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:15284453, ECO:0000305|PubMed:15800637 |
| Chain | Residue | Details |
| A | ASP558 | |
| A | ASP628 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | GLU596 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:15800637 |
| Chain | Residue | Details |
| A | HIS745 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | ASP558 | |
| A | VAL770 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7, ECO:0000269|PubMed:15800637, ECO:0007744|PDB:1Z25 |
| Chain | Residue | Details |
| A | ASP628 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15800637, ECO:0007744|PDB:1Z25 |
| Chain | Residue | Details |
| A | HIS745 |
