1Z1G

Crystal structure of a lambda integrase tetramer bound to a Holliday junction

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006310	biological_process	DNA recombination
A	0008907	molecular_function	integrase activity
A	0015074	biological_process	DNA integration
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0032359	biological_process	provirus excision
A	0044826	biological_process	viral genome integration into host DNA
A	0046718	biological_process	symbiont entry into host cell
A	0075713	biological_process	establishment of integrated proviral latency
B	0003677	molecular_function	DNA binding
B	0006310	biological_process	DNA recombination
B	0008907	molecular_function	integrase activity
B	0015074	biological_process	DNA integration
B	0016740	molecular_function	transferase activity
B	0016787	molecular_function	hydrolase activity
B	0032359	biological_process	provirus excision
B	0044826	biological_process	viral genome integration into host DNA
B	0046718	biological_process	symbiont entry into host cell
B	0075713	biological_process	establishment of integrated proviral latency
C	0003677	molecular_function	DNA binding
C	0006310	biological_process	DNA recombination
C	0008907	molecular_function	integrase activity
C	0015074	biological_process	DNA integration
C	0016740	molecular_function	transferase activity
C	0016787	molecular_function	hydrolase activity
C	0032359	biological_process	provirus excision
C	0044826	biological_process	viral genome integration into host DNA
C	0046718	biological_process	symbiont entry into host cell
C	0075713	biological_process	establishment of integrated proviral latency
D	0003677	molecular_function	DNA binding
D	0006310	biological_process	DNA recombination
D	0008907	molecular_function	integrase activity
D	0015074	biological_process	DNA integration
D	0016740	molecular_function	transferase activity
D	0016787	molecular_function	hydrolase activity
D	0032359	biological_process	provirus excision
D	0044826	biological_process	viral genome integration into host DNA
D	0046718	biological_process	symbiont entry into host cell
D	0075713	biological_process	establishment of integrated proviral latency

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	ARG212
B	HIS333
C	ARG212
C	LYS235
C	HIS308
C	ARG311
C	HIS333
D	ARG212
D	LYS235
D	HIS308
D	ARG311
A	LYS235
D	HIS333
A	HIS308
A	ARG311
A	HIS333
B	ARG212
B	LYS235
B	HIS308
B	ARG311

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01246, ECO:0007744|PDB:1P7D, ECO:0007744|PDB:1Z19, ECO:0007744|PDB:1Z1B

Chain	Residue	Details
A	PHE342
B	PHE342
C	PHE342
D	PHE342

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