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1YZQ

GppNHp-Bound Rab6 GTPase

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 901
ChainResidue
ATHR27
ATHR45
AGNP900
AHOH933

site_idAC2
Number of Residues24
DetailsBINDING SITE FOR RESIDUE GNP A 900
ChainResidue
ATHR27
ASER28
APHE38
AASP39
AASN40
ATYR42
ATHR45
AGLY71
AASN126
ALYS127
AASP129
ALEU130
ASER156
AALA157
ALYS158
AMG901
AHOH933
AHOH934
AHOH942
AGLN22
ASER23
AVAL24
AGLY25
ALYS26

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsMotif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues19
DetailsMotif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues1
DetailsModified residue: {"description":"O-AMP-tyrosine; by Legionella DrrA","evidences":[{"source":"PubMed","id":"21822290","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLN72

240971

PDB entries from 2025-08-27

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