Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 1001 |
| Chain | Residue |
| A | LEU222 |
| A | MET224 |
| A | VAL227 |
| A | HOH2075 |
| A | HOH2137 |
| A | HOH2170 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 1002 |
| Chain | Residue |
| B | HOH2132 |
| B | HOH2133 |
| B | HOH2234 |
| B | LEU222 |
| B | MET224 |
| B | VAL227 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2001 |
| Chain | Residue |
| A | SER17 |
| A | ARG20 |
| A | HOH2041 |
| A | HOH2050 |
| A | HOH2091 |
| A | HOH2274 |
| A | HOH2345 |
| A | HOH2395 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2002 |
| Chain | Residue |
| A | HOH2077 |
| B | SER17 |
| B | ARG20 |
| B | HOH2039 |
| B | HOH2273 |
| B | HOH2347 |
| B | HOH2348 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2003 |
| Chain | Residue |
| A | GLU70 |
| A | ARG80 |
| B | HIS13 |
| B | LYS14 |
| B | HOH2026 |
| B | HOH2366 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2004 |
| Chain | Residue |
| A | ALA170 |
| A | ILE171 |
| A | GLY172 |
| A | SER212 |
| A | GLY233 |
| A | GLY234 |
| A | HOH2017 |
| A | HOH2054 |
| A | HOH2055 |
| A | HOH2271 |
| A | HOH2309 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 B 2005 |
| Chain | Residue |
| B | ILE171 |
| B | GLY172 |
| B | SER212 |
| B | GLY233 |
| B | GLY234 |
| B | HOH2030 |
| B | HOH2037 |
| B | HOH2054 |
| B | HOH2208 |
| B | HOH2275 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2006 |
| Chain | Residue |
| A | HIS68 |
| A | LYS69 |
| A | GLU70 |
| A | HOH2099 |
| A | HOH2396 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 2007 |
| Chain | Residue |
| A | HIS13 |
| A | LYS14 |
| A | HOH2033 |
| B | ARG80 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA164-GLY174 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Electrophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| A | GLY172 | |
| A | GLU166 | |
| A | LYS11 | |
| A | HIS94 | |
| A | ASN9 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| B | GLY172 | |
| B | GLU166 | |
| B | LYS11 | |
| B | HIS94 | |
| B | ASN9 | |
