1YVU
Crystal structure of A. aeolicus Argonaute
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003727 | molecular_function | single-stranded RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035194 | biological_process | regulatory ncRNA-mediated post-transcriptional gene silencing |
| A | 0035198 | molecular_function | miRNA binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 901 |
| Chain | Residue |
| A | ASP502 |
| A | SER504 |
| A | ASP683 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | ASP502 | |
| A | GLU541 | |
| A | ASP571 | |
| A | ASP683 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7, ECO:0000305|PubMed:16061186, ECO:0007744|PDB:1YVU |
| Chain | Residue | Details |
| A | ASP502 | |
| A | ASP683 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | ASP571 |
