1YVF

Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 A 702

Chain	Residue
A	GLY480
A	GLU481
A	ASN483
A	HOH808
A	HOH809

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 701

Chain	Residue
A	GLY480
A	GLY480

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site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PH7 A 800

Chain	Residue
A	CYS366
A	SER368
A	LEU384
A	ASN411
A	MET414
A	GLN446
A	TYR448
A	SER556
A	HOH807
A	HOH811
A	ARG200
A	ASN316

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 600

Chain	Residue
A	ARG168

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	LEU83
A	ARG120
A	TRP123
A	GLU248
A	HOH988

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 602

Chain	Residue
A	ASP319
A	CYS366
A	SER367

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 605

Chain	Residue
A	LEU497

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