1YQU

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006148	biological_process	inosine catabolic process
A	0006149	biological_process	deoxyinosine catabolic process
A	0006152	biological_process	purine nucleoside catabolic process
A	0006161	biological_process	deoxyguanosine catabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0015949	biological_process	nucleobase-containing small molecule interconversion
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0034214	biological_process	protein hexamerization
A	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
A	0042802	molecular_function	identical protein binding
A	0046115	biological_process	guanosine catabolic process
A	0047724	molecular_function	inosine nucleosidase activity
A	0047975	molecular_function	guanosine phosphorylase activity
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	1903228	biological_process	xanthosine catabolic process
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006148	biological_process	inosine catabolic process
B	0006149	biological_process	deoxyinosine catabolic process
B	0006152	biological_process	purine nucleoside catabolic process
B	0006161	biological_process	deoxyguanosine catabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0015949	biological_process	nucleobase-containing small molecule interconversion
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0034214	biological_process	protein hexamerization
B	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
B	0042802	molecular_function	identical protein binding
B	0046115	biological_process	guanosine catabolic process
B	0047724	molecular_function	inosine nucleosidase activity
B	0047975	molecular_function	guanosine phosphorylase activity
B	0055086	biological_process	nucleobase-containing small molecule metabolic process
B	1903228	biological_process	xanthosine catabolic process
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006148	biological_process	inosine catabolic process
C	0006149	biological_process	deoxyinosine catabolic process
C	0006152	biological_process	purine nucleoside catabolic process
C	0006161	biological_process	deoxyguanosine catabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0015949	biological_process	nucleobase-containing small molecule interconversion
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0034214	biological_process	protein hexamerization
C	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
C	0042802	molecular_function	identical protein binding
C	0046115	biological_process	guanosine catabolic process
C	0047724	molecular_function	inosine nucleosidase activity
C	0047975	molecular_function	guanosine phosphorylase activity
C	0055086	biological_process	nucleobase-containing small molecule metabolic process
C	1903228	biological_process	xanthosine catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 500

Chain	Residue
A	GLY33
A	SER34
A	ARG85
A	HIS87
A	ASN116
A	ALA117
A	SER216

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 B 501

Chain	Residue
B	ARG85
B	HIS87
B	ASN116
B	ALA117
B	SER216
B	GLY33
B	SER34

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 C 502

Chain	Residue
C	GLY33
C	SER34
C	ARG85
C	HIS87
C	ASN116
C	ALA117
C	SER216

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN A 400

Chain	Residue
A	ALA117
A	ALA118
A	PHE196
A	GLU197
A	MET215
A	THR238
A	ASN239

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN B 401

Chain	Residue
B	ALA117
B	ALA118
B	PHE196
B	GLU197
B	MET215
B	THR238
B	ASN239

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN C 402

Chain	Residue
C	ALA117
C	ALA118
C	PHE196
C	GLU197
C	MET215
C	THR238
C	ASN239

---

Functional Information from PROSITE/UniProt

site_id	PS01240
Number of Residues	42
Details	PNP_MTAP_2 Purine and other phosphorylases family 2 signature. VcmkGrgHfYegrgMtimTdaIrTfkllGcel.LFctNAaGSL

Chain	Residue	Details
A	VAL80-LEU121

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15808857","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YQQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YQU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15808857","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
A	GLU90
A	HIS87
A	ASN239

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
B	GLU90
B	HIS87
B	ASN239

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
C	GLU90
C	HIS87
C	ASN239

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
A	ASN239

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
B	ASN239

---

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1cg6

Chain	Residue	Details
C	ASN239

---