1YQQ

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006148	biological_process	inosine catabolic process
A	0006149	biological_process	deoxyinosine catabolic process
A	0006152	biological_process	purine nucleoside catabolic process
A	0006161	biological_process	deoxyguanosine catabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0015949	biological_process	nucleobase-containing small molecule interconversion
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0034214	biological_process	protein hexamerization
A	0042802	molecular_function	identical protein binding
A	0046115	biological_process	guanosine catabolic process
A	0047724	molecular_function	inosine nucleosidase activity
A	0047975	molecular_function	guanosine phosphorylase activity
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	1903228	biological_process	xanthosine catabolic process
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006148	biological_process	inosine catabolic process
B	0006149	biological_process	deoxyinosine catabolic process
B	0006152	biological_process	purine nucleoside catabolic process
B	0006161	biological_process	deoxyguanosine catabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0015949	biological_process	nucleobase-containing small molecule interconversion
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0034214	biological_process	protein hexamerization
B	0042802	molecular_function	identical protein binding
B	0046115	biological_process	guanosine catabolic process
B	0047724	molecular_function	inosine nucleosidase activity
B	0047975	molecular_function	guanosine phosphorylase activity
B	0055086	biological_process	nucleobase-containing small molecule metabolic process
B	1903228	biological_process	xanthosine catabolic process
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006148	biological_process	inosine catabolic process
C	0006149	biological_process	deoxyinosine catabolic process
C	0006152	biological_process	purine nucleoside catabolic process
C	0006161	biological_process	deoxyguanosine catabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0015949	biological_process	nucleobase-containing small molecule interconversion
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0034214	biological_process	protein hexamerization
C	0042802	molecular_function	identical protein binding
C	0046115	biological_process	guanosine catabolic process
C	0047724	molecular_function	inosine nucleosidase activity
C	0047975	molecular_function	guanosine phosphorylase activity
C	0055086	biological_process	nucleobase-containing small molecule metabolic process
C	1903228	biological_process	xanthosine catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 500

Chain	Residue
A	SER34
A	HIS65
A	ARG85
A	HIS87
A	ASN116
A	ALA117
A	SER216

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 B 1500

Chain	Residue
B	ARG85
B	HIS87
B	ASN116
B	ALA117
B	SER216
B	HOH1532
B	HOH1535
B	HOH1560
B	SER34
B	HIS65

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 C 2500

Chain	Residue
C	SER34
C	HIS65
C	ARG85
C	HIS87
C	ASN116
C	ALA117
C	SER216

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GUN A 400

Chain	Residue
A	ALA117
A	ALA118
A	GLY119
A	GLU197
A	GLY214
A	MET215
A	THR238
A	ASN239
A	THR254
A	HOH523

---

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GUN B 1400

Chain	Residue
B	ALA117
B	ALA118
B	GLY119
B	GLU197
B	GLY214
B	MET215
B	THR238
B	ASN239
B	THR254
B	HOH1560

---

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GUN C 2400

Chain	Residue
C	ALA117
C	ALA118
C	GLY119
C	GLU197
C	GLY214
C	MET215
C	THR238
C	ASN239
C	THR254
C	HOH2518
C	HOH2527
C	HOH2553

---

Functional Information from PROSITE/UniProt

site_id	PS01240
Number of Residues	42
Details	PNP_MTAP_2 Purine and other phosphorylases family 2 signature. VcmkGrgHfYegrgMtimTdaIrTfkllGcel.LFctNAaGSL

Chain	Residue	Details
A	VAL80-LEU121

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:15808857, ECO:0007744|PDB:1YQQ

Chain	Residue	Details
A	HIS65
B	HIS65
C	HIS65

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:15808857, ECO:0007744|PDB:1YQQ, ECO:0007744|PDB:1YQU

Chain	Residue	Details
B	ARG85
B	ALA117
B	SER216
C	ARG85
C	ALA117
C	SER216
A	ARG85
A	ALA117
A	SER216

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:15808857

Chain	Residue	Details
A	GLU197
A	ASN239
B	GLU197
B	ASN239
C	GLU197
C	ASN239

---