1YQ2
beta-galactosidase from Arthrobacter sp. C2-2 (isoenzyme C2-2-1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005990 | biological_process | lactose catabolic process |
| A | 0009341 | cellular_component | beta-galactosidase complex |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0005990 | biological_process | lactose catabolic process |
| B | 0009341 | cellular_component | beta-galactosidase complex |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004565 | molecular_function | beta-galactosidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0005990 | biological_process | lactose catabolic process |
| C | 0009341 | cellular_component | beta-galactosidase complex |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0004565 | molecular_function | beta-galactosidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0005990 | biological_process | lactose catabolic process |
| D | 0009341 | cellular_component | beta-galactosidase complex |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0030246 | molecular_function | carbohydrate binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| E | 0004565 | molecular_function | beta-galactosidase activity |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0005990 | biological_process | lactose catabolic process |
| E | 0009341 | cellular_component | beta-galactosidase complex |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| E | 0030246 | molecular_function | carbohydrate binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| F | 0004565 | molecular_function | beta-galactosidase activity |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0005990 | biological_process | lactose catabolic process |
| F | 0009341 | cellular_component | beta-galactosidase complex |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| F | 0030246 | molecular_function | carbohydrate binding |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 7001 |
| Chain | Residue |
| A | ALA525 |
| A | GLY527 |
| A | GLY529 |
| A | HOH9069 |
| A | HOH9635 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 7501 |
| Chain | Residue |
| A | HOH9751 |
| A | HOH9788 |
| A | ASP201 |
| A | TRP552 |
| A | PHE585 |
| A | ASP588 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 7511 |
| Chain | Residue |
| A | THR99 |
| A | ASN100 |
| A | ASP199 |
| A | GLN200 |
| A | HOH9678 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 8011 |
| Chain | Residue |
| A | ARG761 |
| A | THR811 |
| A | ARG812 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 8501 |
| Chain | Residue |
| A | ARG228 |
| A | ARG314 |
| A | SER462 |
| A | HOH2036 |
| A | HOH9082 |
| A | HOH9193 |
| A | HOH9673 |
| A | HOH9904 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 A 8511 |
| Chain | Residue |
| A | TRP226 |
| A | LEU227 |
| A | THR229 |
| A | ARG311 |
| A | LYS429 |
| A | ASN430 |
| A | HIS431 |
| A | PRO432 |
| A | ARG463 |
| A | HOH9153 |
| A | HOH9546 |
| A | HOH9895 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG A 9001 |
| Chain | Residue |
| A | TRP203 |
| A | HIS335 |
| A | THR337 |
| A | HIS338 |
| A | PRO339 |
| A | ARG343 |
| A | HIS557 |
| A | GLY558 |
| A | ILE559 |
| A | HOH9463 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 7002 |
| Chain | Residue |
| B | ALA525 |
| B | GLY527 |
| B | GLY529 |
| B | HOH9124 |
| B | HOH9630 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 7502 |
| Chain | Residue |
| B | ASP201 |
| B | TRP552 |
| B | PHE585 |
| B | ASP588 |
| B | HOH9824 |
| B | HOH9825 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 7512 |
| Chain | Residue |
| B | THR99 |
| B | ASN100 |
| B | ASP199 |
| B | GLN200 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 8012 |
| Chain | Residue |
| B | ARG761 |
| B | THR811 |
| B | ARG812 |
| B | HOH9903 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 8502 |
| Chain | Residue |
| B | ARG228 |
| B | ARG314 |
| B | SER462 |
| B | HOH9085 |
| B | HOH9391 |
| B | HOH9612 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE SO4 B 8512 |
| Chain | Residue |
| B | TRP226 |
| B | LEU227 |
| B | ARG228 |
| B | THR229 |
| B | ARG311 |
| B | LYS429 |
| B | ASN430 |
| B | HIS431 |
| B | PRO432 |
| B | ARG463 |
| B | HOH9058 |
| B | HOH9429 |
| B | HOH9450 |
| B | HOH9921 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEG B 9002 |
| Chain | Residue |
| B | HOH9503 |
| B | GLN202 |
| B | TRP203 |
| B | LEU205 |
| B | HIS335 |
| B | THR337 |
| B | HIS338 |
| B | PRO339 |
| B | ARG343 |
| B | HIS557 |
| B | GLY558 |
| B | ILE559 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 7003 |
| Chain | Residue |
| C | ALA525 |
| C | GLY527 |
| C | GLY529 |
| C | HOH9034 |
| C | HOH9817 |
| C | HOH9929 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 7503 |
| Chain | Residue |
| C | TYR98 |
| C | ASP201 |
| C | PHE585 |
| C | ASP588 |
| C | HOH9524 |
| C | HOH9818 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 7513 |
| Chain | Residue |
| C | THR99 |
| C | ASN100 |
| C | ASP199 |
| C | GLN200 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 8013 |
| Chain | Residue |
| C | ARG761 |
| C | THR811 |
| C | ARG812 |
| site_id | CC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 C 8513 |
| Chain | Residue |
| C | TRP226 |
| C | LEU227 |
| C | THR229 |
| C | ARG311 |
| C | LYS429 |
| C | ASN430 |
| C | HIS431 |
| C | PRO432 |
| C | ARG463 |
| C | HOH2112 |
| C | HOH9124 |
| C | HOH9474 |
| C | HOH9579 |
| site_id | CC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG C 9003 |
| Chain | Residue |
| C | GLN202 |
| C | TRP203 |
| C | HIS335 |
| C | THR337 |
| C | HIS338 |
| C | GLY342 |
| C | ARG343 |
| C | HIS557 |
| C | GLY558 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 7004 |
| Chain | Residue |
| D | ALA525 |
| D | GLY527 |
| D | GLY529 |
| D | HOH9445 |
| D | HOH9826 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 7504 |
| Chain | Residue |
| D | TYR98 |
| D | ASP201 |
| D | PHE585 |
| D | ASP588 |
| D | HOH9559 |
| D | HOH9827 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA D 7514 |
| Chain | Residue |
| D | THR99 |
| D | ASN100 |
| D | ASP199 |
| D | GLN200 |
| D | HOH9624 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 8014 |
| Chain | Residue |
| D | ARG761 |
| D | THR811 |
| D | ARG812 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 8504 |
| Chain | Residue |
| D | ARG228 |
| D | ARG314 |
| D | SER462 |
| D | HOH9041 |
| D | HOH9453 |
| D | HOH9683 |
| site_id | CC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE SO4 D 8514 |
| Chain | Residue |
| D | TRP226 |
| D | LEU227 |
| D | ARG228 |
| D | THR229 |
| D | ARG311 |
| D | LYS429 |
| D | ASN430 |
| D | HIS431 |
| D | PRO432 |
| D | ARG463 |
| D | HOH2050 |
| D | HOH9211 |
| D | HOH9489 |
| D | HOH9683 |
| site_id | CC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG D 9004 |
| Chain | Residue |
| D | GLN202 |
| D | TRP203 |
| D | LEU205 |
| D | HIS335 |
| D | THR337 |
| D | HIS338 |
| D | PRO339 |
| D | ARG343 |
| D | HIS557 |
| D | GLY558 |
| D | HOH9746 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG E 7005 |
| Chain | Residue |
| E | ALA525 |
| E | GLY527 |
| E | GLY529 |
| E | HOH9034 |
| E | HOH9801 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA E 7505 |
| Chain | Residue |
| E | TYR98 |
| E | ASP201 |
| E | PHE585 |
| E | ASP588 |
| E | HOH9802 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA E 7515 |
| Chain | Residue |
| E | THR99 |
| E | ASN100 |
| E | ASP199 |
| E | GLN200 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 8015 |
| Chain | Residue |
| E | ARG761 |
| E | THR811 |
| E | ARG812 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 E 8505 |
| Chain | Residue |
| E | ARG228 |
| E | ARG314 |
| E | SER462 |
| E | HOH9047 |
| E | HOH9406 |
| E | HOH9645 |
| site_id | DC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 E 8515 |
| Chain | Residue |
| E | TRP226 |
| E | LEU227 |
| E | ARG228 |
| E | THR229 |
| E | ARG311 |
| E | LYS429 |
| E | ASN430 |
| E | HIS431 |
| E | PRO432 |
| E | ARG463 |
| E | HOH9241 |
| E | HOH9631 |
| E | HOH9974 |
| site_id | DC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG E 9005 |
| Chain | Residue |
| E | GLN202 |
| E | TRP203 |
| E | HIS335 |
| E | THR337 |
| E | HIS338 |
| E | PRO339 |
| E | GLY342 |
| E | ARG343 |
| E | HIS557 |
| E | GLY558 |
| E | ILE559 |
| site_id | DC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 7006 |
| Chain | Residue |
| F | ALA525 |
| F | GLY527 |
| F | GLY529 |
| F | HOH9016 |
| F | HOH9255 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA F 7506 |
| Chain | Residue |
| F | TYR98 |
| F | ASP201 |
| F | PHE585 |
| F | ASP588 |
| F | HOH9502 |
| F | HOH9808 |
| site_id | EC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA F 7516 |
| Chain | Residue |
| F | THR99 |
| F | ASN100 |
| F | ASP199 |
| F | GLN200 |
| F | HOH9930 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F 8016 |
| Chain | Residue |
| F | ARG761 |
| F | THR811 |
| F | ARG812 |
| site_id | EC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 F 8506 |
| Chain | Residue |
| F | ARG228 |
| F | THR229 |
| F | ARG314 |
| F | SER462 |
| F | HOH9617 |
| F | HOH9900 |
| F | HOH9933 |
| site_id | EC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 F 8516 |
| Chain | Residue |
| F | LEU227 |
| F | THR229 |
| F | GLY309 |
| F | ARG311 |
| F | LYS429 |
| F | ASN430 |
| F | PRO432 |
| F | ARG463 |
| F | HOH9130 |
| F | HOH9184 |
| F | HOH9390 |
| F | HOH9933 |
| site_id | EC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG F 9006 |
| Chain | Residue |
| F | GLN202 |
| F | TRP203 |
| F | HIS335 |
| F | THR337 |
| F | HIS338 |
| F | PRO339 |
| F | ARG343 |
| F | HIS557 |
| F | GLY558 |
| F | ILE559 |
| F | HOH9367 |
Functional Information from PROSITE/UniProt
| site_id | PS00608 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DKNHPSIVMWSlg.NE |
| Chain | Residue | Details |
| A | ASP428-GLU442 |
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NaIRTSHYPphprLLdlaDemGFWVI |
| Chain | Residue | Details |
| A | ASN363-ILE388 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| A | GLU521 | |
| A | GLU442 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| B | GLU521 | |
| B | GLU442 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| C | GLU521 | |
| C | GLU442 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| D | GLU521 | |
| D | GLU442 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| E | GLU521 | |
| E | GLU442 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bgl |
| Chain | Residue | Details |
| F | GLU521 | |
| F | GLU442 |
