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1YO5

Analysis of the 2.0A crystal structure of the protein-DNA complex of human PDEF Ets domain bound to the prostate specific antigen regulatory site

Functional Information from GO Data
ChainGOidnamespacecontents
C0003700molecular_functionDNA-binding transcription factor activity
C0006355biological_processregulation of DNA-templated transcription
C0006357biological_processregulation of transcription by RNA polymerase II
C0043565molecular_functionsequence-specific DNA binding
Functional Information from PROSITE/UniProt
site_idPS00345
Number of Residues9
DetailsETS_DOMAIN_1 Ets-domain signature 1. LWQFLKELL
ChainResidueDetails
CLEU251-LEU259

site_idPS00346
Number of Residues16
DetailsETS_DOMAIN_2 Ets-domain signature 2. RpaMnYDkLSRSIRqY
ChainResidueDetails
CARG297-TYR312

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues83
DetailsDNA_BIND: ETS => ECO:0000255|PROSITE-ProRule:PRU00237
ChainResidueDetails
CILE249-VAL332

223532

PDB entries from 2024-08-07

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