1YKF

NADP-DEPENDENT ALCOHOL DEHYDROGENASE FROM THERMOANAEROBIUM BROCKII

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
C	0008270	molecular_function	zinc ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity
D	0008270	molecular_function	zinc ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0050009	molecular_function	isopropanol dehydrogenase (NADP+) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 354

Chain	Residue
A	CYS37
A	SER39
A	HIS59
A	ASP150

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 354

Chain	Residue
B	CYS37
B	HIS59
B	ASP150
B	NAP353

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 354

Chain	Residue
C	SER39
C	HIS59
C	ASP150
C	NAP353
C	CYS37

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 354

Chain	Residue
D	CYS37
D	SER39
D	HIS59
D	ASP150
D	NAP353

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAP A 353

Chain	Residue
A	THR38
A	SER39
A	HIS42
A	ASP150
A	THR154
A	GLY174
A	ILE175
A	GLY176
A	PRO177
A	VAL178
A	SER199
A	ARG200
A	TYR218
A	ALA242
A	VAL265
A	ASN266
A	TYR267

---

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE NAP B 353

Chain	Residue
B	THR38
B	SER39
B	HIS42
B	ASP150
B	THR154
B	GLY174
B	ILE175
B	GLY176
B	PRO177
B	VAL178
B	SER199
B	ARG200
B	TYR218
B	ALA242
B	VAL265
B	ASN266
B	TYR267
B	ZN354

---

site_id	AC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAP C 353

Chain	Residue
C	THR38
C	SER39
C	HIS42
C	ASP150
C	THR154
C	GLY174
C	ILE175
C	GLY176
C	PRO177
C	VAL178
C	SER199
C	ARG200
C	TYR218
C	ILE223
C	ALA242
C	VAL265
C	ASN266
C	TYR267
C	ZN354

---

site_id	AC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE NAP D 353

Chain	Residue
D	SER39
D	HIS42
D	ASP150
D	THR154
D	GLY174
D	ILE175
D	GLY176
D	PRO177
D	VAL178
D	SER199
D	ARG200
D	TYR218
D	ILE223
D	ALA242
D	VAL265
D	ASN266
D	TYR267
D	ZN354

---

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaVGEvvevGseV

Chain	Residue	Details
A	GLY58-VAL72

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20102159","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9836873","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9836873","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1qlh

Chain	Residue	Details
A	HIS42
A	SER39

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1qlh

Chain	Residue	Details
B	HIS42
B	SER39

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1qlh

Chain	Residue	Details
C	HIS42
C	SER39

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1qlh

Chain	Residue	Details
D	HIS42
D	SER39

---