1YJS
K226Q Mutant Of Serine Hydroxymethyltransferase From B. Stearothermophilus, Complex With Glycine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006544 | biological_process | glycine metabolic process |
| A | 0006545 | biological_process | glycine biosynthetic process |
| A | 0006563 | biological_process | L-serine metabolic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019264 | biological_process | glycine biosynthetic process from serine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| A | 0046653 | biological_process | tetrahydrofolate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP A 501 |
| Chain | Residue |
| A | TYR51 |
| A | THR223 |
| A | HIS225 |
| A | GLY256 |
| A | GLY257 |
| A | GLY601 |
| A | HOH624 |
| A | HOH638 |
| A | HOH639 |
| A | SER93 |
| A | GLY94 |
| A | ALA95 |
| A | HIS122 |
| A | SER172 |
| A | ASP197 |
| A | ALA199 |
| A | HIS200 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GLY A 601 |
| Chain | Residue |
| A | SER31 |
| A | TYR51 |
| A | TYR61 |
| A | SER172 |
| A | HIS200 |
| A | GLN226 |
| A | ARG357 |
| A | PLP501 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1cs1 |
| Chain | Residue | Details |
| A | CYS64 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1cs1 |
| Chain | Residue | Details |
| A | GLU65 |
