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1YHL

Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 1401
ChainResidue
AASP98
AASP102
ARIS1400
AMG1403
AHOH1407
AHOH1408

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 1402
ChainResidue
AHOH1411
AHOH1533
AASP250
ARIS1400
AHOH1410

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG A 1403
ChainResidue
AASP98
AASP102
ARIS1400
AMG1401
AHOH1406
AHOH1409
AHOH1532

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 1405
ChainResidue
AHIS141
AHOH1501
AHOH1647

site_idAC5
Number of Residues15
DetailsBINDING SITE FOR RESIDUE DMA A 1301
ChainResidue
AGLY47
ALYS48
ATYR49
APHE50
AARG51
AGLN91
AARG108
ATYR211
APHE246
ALYS264
ALYS362
ARIS1400
AHOH1415
AHOH1424
AHOH1574

site_idAC6
Number of Residues23
DetailsBINDING SITE FOR RESIDUE RIS A 1400
ChainResidue
ALEU95
AASP98
AASP102
AARG107
AGLN167
ALYS207
ATHR208
ATYR211
AASP250
ALYS264
ADMA1301
AMG1401
AMG1402
AMG1403
AHOH1407
AHOH1408
AHOH1409
AHOH1410
AHOH1411
AHOH1440
AHOH1455
AHOH1533
AHOH1663

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. IGeyFQVqDDVmD
ChainResidueDetails
AILE242-ASP254

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DgsvmRRG
ChainResidueDetails
ALEU95-GLY109

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1fps
ChainResidueDetails
AARG107
APHE246

226707

PDB entries from 2024-10-30

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