1YFL

T4Dam in Complex with Sinefungin and 16-mer Oligonucleotide Showing Semi-specific and Specific Contact and Flipped Base

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0006260	biological_process	DNA replication
A	0006298	biological_process	mismatch repair
A	0008168	molecular_function	methyltransferase activity
A	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
A	0009008	molecular_function	DNA-methyltransferase activity
A	0009307	biological_process	DNA restriction-modification system
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation
A	0043565	molecular_function	sequence-specific DNA binding
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
A	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
A	1904047	molecular_function	S-adenosyl-L-methionine binding
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0006260	biological_process	DNA replication
B	0006298	biological_process	mismatch repair
B	0008168	molecular_function	methyltransferase activity
B	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
B	0009008	molecular_function	DNA-methyltransferase activity
B	0009307	biological_process	DNA restriction-modification system
B	0016740	molecular_function	transferase activity
B	0032259	biological_process	methylation
B	0043565	molecular_function	sequence-specific DNA binding
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
B	1904047	molecular_function	S-adenosyl-L-methionine binding
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0006260	biological_process	DNA replication
D	0006298	biological_process	mismatch repair
D	0008168	molecular_function	methyltransferase activity
D	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
D	0009008	molecular_function	DNA-methyltransferase activity
D	0009307	biological_process	DNA restriction-modification system
D	0016740	molecular_function	transferase activity
D	0032259	biological_process	methylation
D	0043565	molecular_function	sequence-specific DNA binding
D	0052031	biological_process	symbiont-mediated perturbation of host defense response
D	0052170	biological_process	symbiont-mediated suppression of host innate immune response
D	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
D	1904047	molecular_function	S-adenosyl-L-methionine binding
E	0003676	molecular_function	nucleic acid binding
E	0003677	molecular_function	DNA binding
E	0006260	biological_process	DNA replication
E	0006298	biological_process	mismatch repair
E	0008168	molecular_function	methyltransferase activity
E	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
E	0009008	molecular_function	DNA-methyltransferase activity
E	0009307	biological_process	DNA restriction-modification system
E	0016740	molecular_function	transferase activity
E	0032259	biological_process	methylation
E	0043565	molecular_function	sequence-specific DNA binding
E	0052031	biological_process	symbiont-mediated perturbation of host defense response
E	0052170	biological_process	symbiont-mediated suppression of host innate immune response
E	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
E	1904047	molecular_function	S-adenosyl-L-methionine binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE SFG A 300

Chain	Residue
A	TYR7
A	ASP50
A	ILE51
A	GLN52
A	LEU155
A	HIS156
A	PHE157
A	ASP171
A	PRO173
A	TYR181
A	PHE184
A	ASN10
G	DA616
A	LYS11
A	PHE32
A	CYS33
A	GLY34
A	GLY35
A	LEU36
A	SER37

---

site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE SFG B 301

Chain	Residue
B	TYR7
B	ASN10
B	LYS11
B	PHE32
B	CYS33
B	GLY34
B	GLY35
B	LEU36
B	SER37
B	ASP50
B	ILE51
B	GLN52
B	LEU155
B	HIS156
B	PHE157
B	ASP171
B	PRO173
B	TYR181
B	PHE184
G	DA608

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SFG D 302

Chain	Residue
D	TYR7
D	GLY9
D	ASN10
D	LYS11
D	PHE32
D	CYS33
D	GLY34
D	GLY35
D	LEU36
D	SER37
D	ASP50
D	ILE51
D	GLN52
D	PHE157
D	ASP171
D	PRO173
D	TYR181
D	PHE184
I	DA616

---

site_id	AC4
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SFG E 303

Chain	Residue
E	TYR7
E	ASN10
E	LYS11
E	PHE32
E	CYS33
E	GLY34
E	GLY35
E	LEU36
E	SER37
E	ASP50
E	ILE51
E	GLN52
E	PHE157
E	ASP171
E	PRO173
E	TYR181
E	PHE184
I	DA608

---

Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. VYVDPPY

Chain	Residue	Details
A	VAL168-TYR174

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PDB","id":"1Q0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Q0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YFJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PDB","id":"1Q0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YFJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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