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1YDN

Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35.

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004419molecular_functionhydroxymethylglutaryl-CoA lyase activity
A0006552biological_processL-leucine catabolic process
A0016829molecular_functionlyase activity
A0016833molecular_functionoxo-acid-lyase activity
A0046872molecular_functionmetal ion binding
A0046951biological_processketone body biosynthetic process
B0003824molecular_functioncatalytic activity
B0004419molecular_functionhydroxymethylglutaryl-CoA lyase activity
B0006552biological_processL-leucine catabolic process
B0016829molecular_functionlyase activity
B0016833molecular_functionoxo-acid-lyase activity
B0046872molecular_functionmetal ion binding
B0046951biological_processketone body biosynthetic process
C0003824molecular_functioncatalytic activity
C0004419molecular_functionhydroxymethylglutaryl-CoA lyase activity
C0006552biological_processL-leucine catabolic process
C0016829molecular_functionlyase activity
C0016833molecular_functionoxo-acid-lyase activity
C0046872molecular_functionmetal ion binding
C0046951biological_processketone body biosynthetic process
D0003824molecular_functioncatalytic activity
D0004419molecular_functionhydroxymethylglutaryl-CoA lyase activity
D0006552biological_processL-leucine catabolic process
D0016829molecular_functionlyase activity
D0016833molecular_functionoxo-acid-lyase activity
D0046872molecular_functionmetal ion binding
D0046951biological_processketone body biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA A 601
ChainResidue
AASP14
AHIS205
AHIS207
AASN247

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA B 602
ChainResidue
BHOH667
BASP14
BHIS205
BHIS207
BASN247
BHOH661

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA C 603
ChainResidue
CASP14
CHIS205
CHIS207
CASN247

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA D 604
ChainResidue
DASP14
DHIS205
DHIS207
DASN247

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PDB entries from 2024-07-24

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