1XZ1

Complex of halothane with apoferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0044754	cellular_component	autolysosome
A	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 1001

Chain	Residue
A	ASP80
A	ASP80
A	HOH2061
A	HOH2061

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 1002

Chain	Residue
A	CD1006
A	GLU130
A	GLU130
A	GLU130
A	CD1006
A	CD1006

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 1003

Chain	Residue
A	HIS49

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 1004

Chain	Residue
A	GLU88

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 1005

Chain	Residue
A	GLU56
A	GLU60
A	HOH2148

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 1006

Chain	Residue
A	GLU130
A	CD1002
A	CD1002
A	CD1002
A	HOH2026
A	HOH2026

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HLT A 2001

Chain	Residue
A	LEU24
A	LEU24
A	TYR28
A	LEU81

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"Catalytic site for iron oxidation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---