1XXH

ATPgS Bound E. Coli Clamp Loader Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0009360	cellular_component	DNA polymerase III complex
A	0030894	cellular_component	replisome
A	0043846	cellular_component	DNA polymerase III, clamp loader complex
A	0071897	biological_process	DNA biosynthetic process
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
B	0009360	cellular_component	DNA polymerase III complex
B	0016887	molecular_function	ATP hydrolysis activity
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0005524	molecular_function	ATP binding
C	0006260	biological_process	DNA replication
C	0009360	cellular_component	DNA polymerase III complex
C	0016887	molecular_function	ATP hydrolysis activity
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005524	molecular_function	ATP binding
D	0006260	biological_process	DNA replication
D	0009360	cellular_component	DNA polymerase III complex
D	0016887	molecular_function	ATP hydrolysis activity
E	0003677	molecular_function	DNA binding
E	0003887	molecular_function	DNA-directed DNA polymerase activity
E	0005515	molecular_function	protein binding
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0008408	molecular_function	3'-5' exonuclease activity
E	0009360	cellular_component	DNA polymerase III complex
E	0030894	cellular_component	replisome
E	0043846	cellular_component	DNA polymerase III, clamp loader complex
E	0071897	biological_process	DNA biosynthetic process
F	0003677	molecular_function	DNA binding
F	0003887	molecular_function	DNA-directed DNA polymerase activity
F	0005515	molecular_function	protein binding
F	0006260	biological_process	DNA replication
F	0006261	biological_process	DNA-templated DNA replication
F	0009360	cellular_component	DNA polymerase III complex
F	0030894	cellular_component	replisome
F	0043846	cellular_component	DNA polymerase III, clamp loader complex
F	0071897	biological_process	DNA biosynthetic process
G	0003677	molecular_function	DNA binding
G	0003887	molecular_function	DNA-directed DNA polymerase activity
G	0005524	molecular_function	ATP binding
G	0006260	biological_process	DNA replication
G	0009360	cellular_component	DNA polymerase III complex
G	0016887	molecular_function	ATP hydrolysis activity
H	0003677	molecular_function	DNA binding
H	0003887	molecular_function	DNA-directed DNA polymerase activity
H	0005524	molecular_function	ATP binding
H	0006260	biological_process	DNA replication
H	0009360	cellular_component	DNA polymerase III complex
H	0016887	molecular_function	ATP hydrolysis activity
I	0003677	molecular_function	DNA binding
I	0003887	molecular_function	DNA-directed DNA polymerase activity
I	0005524	molecular_function	ATP binding
I	0006260	biological_process	DNA replication
I	0009360	cellular_component	DNA polymerase III complex
I	0016887	molecular_function	ATP hydrolysis activity
J	0003677	molecular_function	DNA binding
J	0003887	molecular_function	DNA-directed DNA polymerase activity
J	0005515	molecular_function	protein binding
J	0006260	biological_process	DNA replication
J	0006261	biological_process	DNA-templated DNA replication
J	0008408	molecular_function	3'-5' exonuclease activity
J	0009360	cellular_component	DNA polymerase III complex
J	0030894	cellular_component	replisome
J	0043846	cellular_component	DNA polymerase III, clamp loader complex
J	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 401

Chain	Residue
C	CYS64
C	CYS73
C	CYS76
C	CYS79

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 402

Chain	Residue
D	CYS64
D	CYS73
D	GLY74
D	CYS76
D	CYS79

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 403

Chain	Residue
B	CYS64
B	CYS73
B	GLY74
B	CYS76
B	CYS79

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN E 404

Chain	Residue
E	CYS50
E	SER58
E	CYS59
E	GLY60
E	CYS62
E	CYS65

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN H 405

Chain	Residue
H	CYS64
H	THR66
H	CYS73
H	CYS76
H	CYS79

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN I 406

Chain	Residue
I	CYS64
I	CYS73
I	GLY74
I	CYS76
I	CYS79

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN G 407

Chain	Residue
G	CYS64
G	CYS73
G	GLY74
G	CYS76
G	CYS79

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 408

Chain	Residue
J	CYS50
J	CYS59
J	CYS62
J	CYS65

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 C 1300

Chain	Residue
C	THR46
C	ARG47
C	GLY48
C	VAL49
C	LYS51
C	THR52
C	ARG215

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 H 1400

Chain	Residue
H	THR46
H	ARG47
H	GLY48
H	VAL49
H	LYS51
H	THR52
H	ARG215

---

site_id	BC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE AGS D 801

Chain	Residue
D	ALA7
D	ARG11
D	PRO12
D	VAL19
D	ARG47
D	GLY48
D	VAL49
D	GLY50
D	LYS51
D	THR52
D	SER53
D	THR157
D	LEU214
D	ARG215
D	LEU218

---

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE AGS B 802

Chain	Residue
B	ALA7
B	ARG11
B	VAL19
B	THR46
B	ARG47
B	GLY48
B	VAL49
B	GLY50
B	LYS51
B	THR52
B	SER53
B	THR157
B	LEU214
B	ARG215

---

site_id	BC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE AGS I 803

Chain	Residue
I	ALA7
I	TRP10
I	ARG11
I	PRO12
I	VAL19
I	ARG47
I	GLY48
I	VAL49
I	GLY50
I	LYS51
I	THR52
I	SER53
I	LEU178
I	LEU214
I	ARG215

---

site_id	BC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AGS G 804

Chain	Residue
G	ARG11
G	PRO12
G	VAL18
G	VAL19
G	ARG47
G	GLY48
G	VAL49
G	GLY50
G	LYS51
G	THR52
G	SER53
G	LEU214
G	ARG215
G	LEU218
G	ALA7
G	TRP10

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
B	GLY45
C	GLY45
D	GLY45
G	GLY45
H	GLY45
I	GLY45

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:11525729, ECO:0007744|PDB:1JR3

Chain	Residue	Details
B	CYS64
D	CYS73
D	CYS76
D	CYS79
G	CYS64
G	CYS73
G	CYS76
G	CYS79
H	CYS64
H	CYS73
H	CYS76
B	CYS73
H	CYS79
I	CYS64
I	CYS73
I	CYS76
I	CYS79
B	CYS76
B	CYS79
C	CYS64
C	CYS73
C	CYS76
C	CYS79
D	CYS64

---