1XU2
The crystal structure of APRIL bound to BCMA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| B | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
| D | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| D | 0006955 | biological_process | immune response |
| D | 0016020 | cellular_component | membrane |
| R | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| R | 0038023 | molecular_function | signaling receptor activity |
| S | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| S | 0038023 | molecular_function | signaling receptor activity |
| T | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| T | 0038023 | molecular_function | signaling receptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI B 301 |
| Chain | Residue |
| A | HIS106 |
| B | HIS106 |
| D | HIS106 |
Functional Information from PROSITE/UniProt
| site_id | PS00251 |
| Number of Residues | 17 |
| Details | THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. VrVWdTGIYLLysQVlF |
| Chain | Residue | Details |
| A | VAL146-PHE162 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 402 |
| Details | Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"TNFR-Cys"} |
| Chain | Residue | Details |
