1XU1

The crystal structure of APRIL bound to TACI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
D	0005164	molecular_function	tumor necrosis factor receptor binding
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane
R	0005886	cellular_component	plasma membrane
S	0005886	cellular_component	plasma membrane
T	0005886	cellular_component	plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI A 101

Chain	Residue
A	HIS106
A	HOH242
B	HIS106
D	HIS106
D	HOH253
D	HOH281

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Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. VrVWdTGIYLLysQVlF

Chain	Residue	Details
A	VAL146-PHE162

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	402
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	34
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

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