1XTU
Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) and cytidine 5'-triphosphate (CTP)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| A | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006178 | biological_process | guanine salvage |
| A | 0006223 | biological_process | uracil salvage |
| A | 0032263 | biological_process | GMP salvage |
| A | 0032264 | biological_process | IMP salvage |
| A | 0044206 | biological_process | UMP salvage |
| A | 0046100 | biological_process | hypoxanthine metabolic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| B | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006178 | biological_process | guanine salvage |
| B | 0006223 | biological_process | uracil salvage |
| B | 0032263 | biological_process | GMP salvage |
| B | 0032264 | biological_process | IMP salvage |
| B | 0044206 | biological_process | UMP salvage |
| B | 0046100 | biological_process | hypoxanthine metabolic process |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| C | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006178 | biological_process | guanine salvage |
| C | 0006223 | biological_process | uracil salvage |
| C | 0032263 | biological_process | GMP salvage |
| C | 0032264 | biological_process | IMP salvage |
| C | 0044206 | biological_process | UMP salvage |
| C | 0046100 | biological_process | hypoxanthine metabolic process |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| D | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006178 | biological_process | guanine salvage |
| D | 0006223 | biological_process | uracil salvage |
| D | 0032263 | biological_process | GMP salvage |
| D | 0032264 | biological_process | IMP salvage |
| D | 0044206 | biological_process | UMP salvage |
| D | 0046100 | biological_process | hypoxanthine metabolic process |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| E | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0006178 | biological_process | guanine salvage |
| E | 0006223 | biological_process | uracil salvage |
| E | 0032263 | biological_process | GMP salvage |
| E | 0032264 | biological_process | IMP salvage |
| E | 0044206 | biological_process | UMP salvage |
| E | 0046100 | biological_process | hypoxanthine metabolic process |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| F | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| F | 0005829 | cellular_component | cytosol |
| F | 0006178 | biological_process | guanine salvage |
| F | 0006223 | biological_process | uracil salvage |
| F | 0032263 | biological_process | GMP salvage |
| F | 0032264 | biological_process | IMP salvage |
| F | 0044206 | biological_process | UMP salvage |
| F | 0046100 | biological_process | hypoxanthine metabolic process |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| G | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| G | 0005829 | cellular_component | cytosol |
| G | 0006178 | biological_process | guanine salvage |
| G | 0006223 | biological_process | uracil salvage |
| G | 0032263 | biological_process | GMP salvage |
| G | 0032264 | biological_process | IMP salvage |
| G | 0044206 | biological_process | UMP salvage |
| G | 0046100 | biological_process | hypoxanthine metabolic process |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| H | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| H | 0005829 | cellular_component | cytosol |
| H | 0006178 | biological_process | guanine salvage |
| H | 0006223 | biological_process | uracil salvage |
| H | 0032263 | biological_process | GMP salvage |
| H | 0032264 | biological_process | IMP salvage |
| H | 0044206 | biological_process | UMP salvage |
| H | 0046100 | biological_process | hypoxanthine metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P A 1250 |
| Chain | Residue |
| A | ARG105 |
| A | GLY201 |
| A | TYR202 |
| A | ILE203 |
| A | GLY208 |
| A | ASP209 |
| A | ALA210 |
| A | ASP140 |
| A | MET142 |
| A | ILE143 |
| A | ALA144 |
| A | THR145 |
| A | ALA146 |
| A | SER147 |
| A | THR148 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P B 2250 |
| Chain | Residue |
| B | ARG105 |
| B | ASP140 |
| B | MET142 |
| B | ILE143 |
| B | ALA144 |
| B | THR145 |
| B | ALA146 |
| B | SER147 |
| B | THR148 |
| B | GLY201 |
| B | TYR202 |
| B | ILE203 |
| B | GLY208 |
| B | ASP209 |
| B | ALA210 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P C 3250 |
| Chain | Residue |
| C | ARG105 |
| C | ASP140 |
| C | MET142 |
| C | ILE143 |
| C | ALA144 |
| C | THR145 |
| C | ALA146 |
| C | SER147 |
| C | THR148 |
| C | GLY201 |
| C | TYR202 |
| C | ILE203 |
| C | GLY208 |
| C | ASP209 |
| C | ALA210 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P D 4250 |
| Chain | Residue |
| D | ARG105 |
| D | ASP140 |
| D | MET142 |
| D | ILE143 |
| D | ALA144 |
| D | THR145 |
| D | ALA146 |
| D | SER147 |
| D | THR148 |
| D | GLY201 |
| D | TYR202 |
| D | ILE203 |
| D | GLY208 |
| D | ASP209 |
| D | ALA210 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P E 5250 |
| Chain | Residue |
| E | ARG105 |
| E | ASP140 |
| E | MET142 |
| E | ILE143 |
| E | ALA144 |
| E | THR145 |
| E | ALA146 |
| E | SER147 |
| E | THR148 |
| E | GLY201 |
| E | TYR202 |
| E | ILE203 |
| E | GLY208 |
| E | ASP209 |
| E | ALA210 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P F 6250 |
| Chain | Residue |
| F | ARG105 |
| F | ASP140 |
| F | MET142 |
| F | ILE143 |
| F | ALA144 |
| F | THR145 |
| F | ALA146 |
| F | SER147 |
| F | THR148 |
| F | GLY201 |
| F | TYR202 |
| F | ILE203 |
| F | GLY208 |
| F | ASP209 |
| F | ALA210 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P G 7250 |
| Chain | Residue |
| G | GLY201 |
| G | TYR202 |
| G | ILE203 |
| G | GLY208 |
| G | ASP209 |
| G | ALA210 |
| G | ARG105 |
| G | ASP140 |
| G | MET142 |
| G | ILE143 |
| G | ALA144 |
| G | THR145 |
| G | ALA146 |
| G | SER147 |
| G | THR148 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE U5P H 8250 |
| Chain | Residue |
| H | ARG105 |
| H | ASP140 |
| H | MET142 |
| H | ILE143 |
| H | ALA144 |
| H | THR145 |
| H | ALA146 |
| H | SER147 |
| H | THR148 |
| H | GLY201 |
| H | TYR202 |
| H | ILE203 |
| H | GLY208 |
| H | ASP209 |
| H | ALA210 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CTP A 1260 |
| Chain | Residue |
| A | ARG29 |
| A | LYS30 |
| A | VAL33 |
| A | ARG37 |
| A | GLU87 |
| D | CTP4260 |
| E | ARG37 |
| E | LYS91 |
| E | CTP5260 |
| H | GLU87 |
| H | LEU90 |
| H | LYS91 |
| H | PRO94 |
| H | ALA96 |
| H | CTP8260 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CTP G 2260 |
| Chain | Residue |
| B | ARG29 |
| B | LYS30 |
| B | VAL33 |
| B | ARG37 |
| B | GLU87 |
| C | CTP3260 |
| F | ARG37 |
| F | LYS91 |
| F | CTP6260 |
| G | GLU87 |
| G | LEU90 |
| G | LYS91 |
| G | PRO94 |
| G | ALA96 |
| G | CTP7260 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CTP C 3260 |
| Chain | Residue |
| C | ARG29 |
| C | LYS30 |
| C | VAL33 |
| C | ARG37 |
| C | GLU87 |
| F | GLU87 |
| F | LYS91 |
| F | PRO94 |
| F | ALA96 |
| F | CTP6260 |
| G | ARG37 |
| G | LYS91 |
| G | CTP2260 |
| G | CTP7260 |
| site_id | BC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CTP D 4260 |
| Chain | Residue |
| A | CTP1260 |
| D | ARG29 |
| D | LYS30 |
| D | VAL33 |
| D | ARG37 |
| D | GLU87 |
| E | GLU87 |
| E | LYS91 |
| E | PRO94 |
| E | ALA96 |
| E | CTP5260 |
| H | ARG37 |
| H | LYS91 |
| H | CTP8260 |
| site_id | BC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CTP E 5260 |
| Chain | Residue |
| A | LYS91 |
| A | CTP1260 |
| D | GLU87 |
| D | LYS91 |
| D | PRO94 |
| D | ALA96 |
| D | CTP4260 |
| E | ARG29 |
| E | LYS30 |
| E | VAL33 |
| E | ARG37 |
| E | GLU87 |
| H | CTP8260 |
| site_id | BC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CTP F 6260 |
| Chain | Residue |
| B | ARG37 |
| B | LYS91 |
| C | GLU87 |
| C | LYS91 |
| C | PRO94 |
| C | ALA96 |
| C | CTP3260 |
| F | ARG29 |
| F | LYS30 |
| F | VAL33 |
| F | ARG37 |
| F | GLU87 |
| G | CTP2260 |
| G | CTP7260 |
| site_id | BC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CTP G 7260 |
| Chain | Residue |
| B | GLU87 |
| B | LEU90 |
| B | LYS91 |
| B | PRO94 |
| B | ALA96 |
| C | ARG37 |
| C | LYS91 |
| C | CTP3260 |
| F | CTP6260 |
| G | ARG29 |
| G | LYS30 |
| G | VAL33 |
| G | ARG37 |
| G | GLU87 |
| G | CTP2260 |
| site_id | BC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CTP H 8260 |
| Chain | Residue |
| A | GLU87 |
| A | LEU90 |
| A | LYS91 |
| A | PRO94 |
| A | ALA96 |
| A | CTP1260 |
| D | ARG37 |
| D | LYS91 |
| D | CTP4260 |
| E | CTP5260 |
| H | ARG29 |
| H | LYS30 |
| H | VAL33 |
| H | ARG37 |
| H | GLU87 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 232 |
| Details | Binding site: {} |
| Chain | Residue | Details |
