1XTT

Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
A	0004845	molecular_function	uracil phosphoribosyltransferase activity
A	0005525	molecular_function	GTP binding
A	0005829	cellular_component	cytosol
A	0006178	biological_process	guanine salvage
A	0006223	biological_process	uracil salvage
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0032263	biological_process	GMP salvage
A	0032264	biological_process	IMP salvage
A	0044206	biological_process	UMP salvage
A	0046100	biological_process	hypoxanthine metabolic process
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
B	0004845	molecular_function	uracil phosphoribosyltransferase activity
B	0005525	molecular_function	GTP binding
B	0005829	cellular_component	cytosol
B	0006178	biological_process	guanine salvage
B	0006223	biological_process	uracil salvage
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0032263	biological_process	GMP salvage
B	0032264	biological_process	IMP salvage
B	0044206	biological_process	UMP salvage
B	0046100	biological_process	hypoxanthine metabolic process
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
C	0004845	molecular_function	uracil phosphoribosyltransferase activity
C	0005525	molecular_function	GTP binding
C	0005829	cellular_component	cytosol
C	0006178	biological_process	guanine salvage
C	0006223	biological_process	uracil salvage
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0032263	biological_process	GMP salvage
C	0032264	biological_process	IMP salvage
C	0044206	biological_process	UMP salvage
C	0046100	biological_process	hypoxanthine metabolic process
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
D	0004845	molecular_function	uracil phosphoribosyltransferase activity
D	0005525	molecular_function	GTP binding
D	0005829	cellular_component	cytosol
D	0006178	biological_process	guanine salvage
D	0006223	biological_process	uracil salvage
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0032263	biological_process	GMP salvage
D	0032264	biological_process	IMP salvage
D	0044206	biological_process	UMP salvage
D	0046100	biological_process	hypoxanthine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE U5P A 1250

Chain	Residue
A	ARG105
A	TYR202
A	ILE203
A	GLY208
A	ASP209
A	ALA210
A	HOH1251
A	HOH1252
A	HOH1265
A	HOH1277
A	HOH1289
A	ASP140
A	MET142
A	ALA144
A	THR145
A	ALA146
A	SER147
A	THR148
A	GLY201

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site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE U5P B 2250

Chain	Residue
B	ARG80
B	ASP140
B	MET142
B	ALA144
B	THR145
B	ALA146
B	SER147
B	THR148
B	GLY201
B	TYR202
B	ILE203
B	GLY208
B	ASP209
B	ALA210
B	HOH2254
B	HOH2256
B	HOH2263
B	HOH2280
B	HOH2306

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE U5P C 3250

Chain	Residue
C	ARG105
C	ASP140
C	MET142
C	ALA144
C	THR145
C	ALA146
C	SER147
C	THR148
C	GLY201
C	TYR202
C	ILE203
C	GLY208
C	ASP209
C	ALA210
C	HOH3251
C	HOH3253
C	HOH3257
C	HOH3262

---

site_id	AC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE U5P D 4250

Chain	Residue
D	ARG80
D	ARG105
D	ASP140
D	MET142
D	ALA144
D	THR145
D	ALA146
D	SER147
D	THR148
D	GLY201
D	TYR202
D	ILE203
D	GLY208
D	ASP209
D	ALA210
D	HOH4254
D	HOH4266
D	HOH4269
D	HOH4276
D	HOH4318

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site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACY B 2252

Chain	Residue
B	ASN77
B	ILE78
B	LEU79
B	ARG80
B	ALA81
B	ALA82
B	VAL83
B	PHE215
C	TYR123

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACY D 4252

Chain	Residue
A	TYR123
D	ASN77
D	ILE78
D	LEU79
D	ARG80
D	ALA81
D	ALA82
D	VAL83
D	PHE215

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	116
Details	Binding site: {}

Chain

Residue

Details

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