1XRH

Crystal Structure of Ureidoglycolate Dehydrogenase from Escherichia Coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000256	biological_process	allantoin catabolic process
A	0005737	cellular_component	cytoplasm
A	0006144	biological_process	purine nucleobase metabolic process
A	0009040	molecular_function	ureidoglycolate dehydrogenase activity
A	0009442	biological_process	allantoin assimilation pathway
A	0016491	molecular_function	oxidoreductase activity
B	0000256	biological_process	allantoin catabolic process
B	0005737	cellular_component	cytoplasm
B	0006144	biological_process	purine nucleobase metabolic process
B	0009040	molecular_function	ureidoglycolate dehydrogenase activity
B	0009442	biological_process	allantoin assimilation pathway
B	0016491	molecular_function	oxidoreductase activity
C	0000256	biological_process	allantoin catabolic process
C	0005737	cellular_component	cytoplasm
C	0006144	biological_process	purine nucleobase metabolic process
C	0009040	molecular_function	ureidoglycolate dehydrogenase activity
C	0009442	biological_process	allantoin assimilation pathway
C	0016491	molecular_function	oxidoreductase activity
D	0000256	biological_process	allantoin catabolic process
D	0005737	cellular_component	cytoplasm
D	0006144	biological_process	purine nucleobase metabolic process
D	0009040	molecular_function	ureidoglycolate dehydrogenase activity
D	0009442	biological_process	allantoin assimilation pathway
D	0016491	molecular_function	oxidoreductase activity
E	0000256	biological_process	allantoin catabolic process
E	0005737	cellular_component	cytoplasm
E	0006144	biological_process	purine nucleobase metabolic process
E	0009040	molecular_function	ureidoglycolate dehydrogenase activity
E	0009442	biological_process	allantoin assimilation pathway
E	0016491	molecular_function	oxidoreductase activity
F	0000256	biological_process	allantoin catabolic process
F	0005737	cellular_component	cytoplasm
F	0006144	biological_process	purine nucleobase metabolic process
F	0009040	molecular_function	ureidoglycolate dehydrogenase activity
F	0009442	biological_process	allantoin assimilation pathway
F	0016491	molecular_function	oxidoreductase activity
G	0000256	biological_process	allantoin catabolic process
G	0005737	cellular_component	cytoplasm
G	0006144	biological_process	purine nucleobase metabolic process
G	0009040	molecular_function	ureidoglycolate dehydrogenase activity
G	0009442	biological_process	allantoin assimilation pathway
G	0016491	molecular_function	oxidoreductase activity
H	0000256	biological_process	allantoin catabolic process
H	0005737	cellular_component	cytoplasm
H	0006144	biological_process	purine nucleobase metabolic process
H	0009040	molecular_function	ureidoglycolate dehydrogenase activity
H	0009442	biological_process	allantoin assimilation pathway
H	0016491	molecular_function	oxidoreductase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:23284870

Chain	Residue	Details
A	HIS118
B	HIS118
C	HIS118
D	HIS118
E	HIS118
F	HIS118
G	HIS118
H	HIS118

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site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: BINDING => ECO:0000305|PubMed:23284870, ECO:0007744|PDB:4H8A

Chain	Residue	Details
A	SER142
C	ASP176
C	LYS226
C	GLY308
D	SER142
D	ASP176
D	LYS226
D	GLY308
E	SER142
E	ASP176
E	LYS226
A	ASP176
E	GLY308
F	SER142
F	ASP176
F	LYS226
F	GLY308
G	SER142
G	ASP176
G	LYS226
G	GLY308
H	SER142
A	LYS226
H	ASP176
H	LYS226
H	GLY308
A	GLY308
B	SER142
B	ASP176
B	LYS226
B	GLY308
C	SER142

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site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Plays a crucial role in stabilizing the binding of (S)-ureidoglycolate => ECO:0000305|PubMed:23284870

Chain	Residue	Details
A	ARG50
B	ARG50
C	ARG50
D	ARG50
E	ARG50
F	ARG50
G	ARG50
H	ARG50

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
A	HIS46

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
B	HIS46

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site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
C	HIS46

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site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
D	HIS46

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site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
E	HIS46

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site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
F	HIS46

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site_id	CSA7
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
G	HIS46

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site_id	CSA8
Number of Residues	1
Details	Annotated By Reference To The Literature 1s20

Chain	Residue	Details
H	HIS46

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