Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000702 | molecular_function | oxidized base lesion DNA N-glycosylase activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0016829 | molecular_function | lyase activity |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 8HG A 257 |
| Chain | Residue |
| A | GLN31 |
| A | TRP222 |
| A | HOH272 |
| A | SER58 |
| A | TYR59 |
| A | TRP69 |
| A | LYS140 |
| A | PHE144 |
| A | PRO170 |
| A | ASP172 |
| A | ASP218 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 8HG A 258 |
| Chain | Residue |
| A | CYS85 |
| A | CYS85 |
| A | ARG86 |
| A | LEU89 |
| A | LYS106 |
| A | LEU110 |
| A | HOH300 |
| A | HOH485 |
| A | HOH485 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 59 |
| Details | Region: {"description":"Helix-hairpin-helix"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Schiff-base intermediate with DNA"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
