1XOX
SOLUTION STRUCTURE OF HUMAN SURVIVIN
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 998 |
| Chain | Residue |
| B | CYS57 |
| B | PHE58 |
| B | CYS60 |
| B | HIS77 |
| B | CYS84 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 999 |
| Chain | Residue |
| A | CYS84 |
| A | CYS57 |
| A | PHE58 |
| A | CYS60 |
| A | HIS77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17956729, ECO:0007744|PDB:2QFA |
| Chain | Residue | Details |
| A | CYS57 | |
| A | CYS60 | |
| A | HIS77 | |
| A | CYS84 | |
| B | CYS57 | |
| B | CYS60 | |
| B | HIS77 | |
| B | CYS84 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by AURKC => ECO:0000269|PubMed:27332895 |
| Chain | Residue | Details |
| A | SER20 | |
| B | SER20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:20826784 |
| Chain | Residue | Details |
| A | LYS23 | |
| B | LYS115 | |
| A | LYS90 | |
| A | LYS110 | |
| A | LYS112 | |
| A | LYS115 | |
| B | LYS23 | |
| B | LYS90 | |
| B | LYS110 | |
| B | LYS112 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by CDK1 and CDK15 => ECO:0000269|PubMed:11069302, ECO:0000269|PubMed:24866247, ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR34 | |
| B | THR34 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by CK2; in vitro => ECO:0000269|PubMed:21252625 |
| Chain | Residue | Details |
| A | THR48 | |
| B | THR48 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by AURKB => ECO:0000269|PubMed:14610074 |
| Chain | Residue | Details |
| A | THR117 | |
| B | THR117 |
