Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1XMF

Structure of Mn(II)-Soaked Apo Methane Monooxygenase Hydroxylase Crystals from M. capsulatus (Bath)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0006730	biological_process	one-carbon metabolic process
A	0015049	molecular_function	methane monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0106317	molecular_function	methane monooxygenase NADH activity
A	0106318	molecular_function	methane monooxygenase NADPH activity
B	0004497	molecular_function	monooxygenase activity
B	0005515	molecular_function	protein binding
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0006730	biological_process	one-carbon metabolic process
B	0015049	molecular_function	methane monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0106317	molecular_function	methane monooxygenase NADH activity
B	0106318	molecular_function	methane monooxygenase NADPH activity
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0006725	biological_process	obsolete cellular aromatic compound metabolic process
C	0006730	biological_process	one-carbon metabolic process
C	0015049	molecular_function	methane monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
C	0106317	molecular_function	methane monooxygenase NADH activity
C	0106318	molecular_function	methane monooxygenase NADPH activity
D	0004497	molecular_function	monooxygenase activity
D	0005515	molecular_function	protein binding
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0006730	biological_process	one-carbon metabolic process
D	0015049	molecular_function	methane monooxygenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
D	0106317	molecular_function	methane monooxygenase NADH activity
D	0106318	molecular_function	methane monooxygenase NADPH activity
E	0004497	molecular_function	monooxygenase activity
E	0006730	biological_process	one-carbon metabolic process
E	0015049	molecular_function	methane monooxygenase activity
E	0015947	biological_process	methane metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0106317	molecular_function	methane monooxygenase NADH activity
E	0106318	molecular_function	methane monooxygenase NADPH activity
F	0004497	molecular_function	monooxygenase activity
F	0006730	biological_process	one-carbon metabolic process
F	0015049	molecular_function	methane monooxygenase activity
F	0015947	biological_process	methane metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0106317	molecular_function	methane monooxygenase NADH activity
F	0106318	molecular_function	methane monooxygenase NADPH activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN A 5001

Chain	Residue
A	GLU114
A	GLU144
A	HIS147
A	GLU243
A	MN5002
A	HOH5122
A	HOH5125

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN A 5002

Chain	Residue
A	GLU209
A	GLU243
A	HIS246
A	MN5001
A	HOH5122
A	GLN140
A	GLU144

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN B 5003

Chain	Residue
B	GLU114
B	GLU144
B	HIS147
B	GLU243
B	MN5004
B	HOH5102
B	HOH5215

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 5004

Chain	Residue
B	GLU144
B	GLU209
B	GLU243
B	HIS246
B	MN5003
B	HOH5215

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C 5005

Chain	Residue
C	ASP348
C	HOH5169
C	HOH5178

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CA A 5006

Chain	Residue
A	ASN527
A	HOH5127
A	HOH5129
A	HOH5132
A	HOH5151
B	ASN412
B	SER428
E	HOH305

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA C 5007

Chain	Residue
C	ASP376
C	ASP378
C	HOH5182

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 5008

Chain	Residue
C	GLU222
C	HOH5145
C	HOH5159
C	HOH5167

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255

Chain	Residue	Details
A	CYS151
B	CYS151

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	GLU114
B	GLU209
B	GLU243
B	HIS246
A	GLU144
A	HIS147
A	GLU209
A	GLU243
A	HIS246
B	GLU114
B	GLU144
B	HIS147

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)