1XKY
Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0044281 | biological_process | small molecule metabolic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0044281 | biological_process | small molecule metabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| C | 0009085 | biological_process | lysine biosynthetic process |
| C | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019877 | biological_process | diaminopimelate biosynthetic process |
| C | 0044281 | biological_process | small molecule metabolic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| D | 0009085 | biological_process | lysine biosynthetic process |
| D | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019877 | biological_process | diaminopimelate biosynthetic process |
| D | 0044281 | biological_process | small molecule metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 1801 |
| Chain | Residue |
| C | SER154 |
| C | ILE156 |
| C | GLU157 |
| C | ILE159 |
| C | HOH1971 |
| C | HOH2132 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1802 |
| Chain | Residue |
| B | PHE183 |
| B | HOH1888 |
| B | HOH1910 |
| B | ILE176 |
| B | THR179 |
| B | ALA180 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1803 |
| Chain | Residue |
| B | SER154 |
| B | ILE156 |
| B | GLU157 |
| B | ILE159 |
| B | HOH1942 |
| B | HOH1946 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K D 1804 |
| Chain | Residue |
| D | ILE176 |
| D | THR179 |
| D | ALA180 |
| D | PHE183 |
| D | HOH1911 |
| D | HOH1965 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 1805 |
| Chain | Residue |
| C | ILE176 |
| C | THR179 |
| C | ALA180 |
| C | PHE183 |
| C | HOH1916 |
| C | HOH1940 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1806 |
| Chain | Residue |
| A | ILE176 |
| A | THR179 |
| A | ALA180 |
| A | PHE183 |
| A | HOH1896 |
| A | HOH1956 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1807 |
| Chain | Residue |
| A | SER154 |
| A | ILE156 |
| A | GLU157 |
| A | ILE159 |
| A | HOH1911 |
| A | HOH1917 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K D 1808 |
| Chain | Residue |
| D | SER154 |
| D | ILE156 |
| D | GLU157 |
| D | ILE159 |
| D | HOH1967 |
| D | HOH2111 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K B 1809 |
| Chain | Residue |
| B | ILE176 |
| B | GLU177 |
| B | THR179 |
| B | HOH1888 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K C 1810 |
| Chain | Residue |
| C | ILE176 |
| C | GLU177 |
| C | THR179 |
| C | HOH1940 |
Functional Information from PROSITE/UniProt
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| A | TYR135 | |
| A | ARG140 | |
| A | LYS163 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| B | TYR135 | |
| B | ARG140 | |
| B | LYS163 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| C | TYR135 | |
| C | ARG140 | |
| C | LYS163 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| D | TYR135 | |
| D | ARG140 | |
| D | LYS163 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| A | THR47 | |
| A | THR46 | |
| A | LYS163 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| B | THR47 | |
| B | THR46 | |
| B | LYS163 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| C | THR47 | |
| C | THR46 | |
| C | LYS163 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| D | THR47 | |
| D | THR46 | |
| D | LYS163 |
