1XKL
Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002376 | biological_process | immune system process |
| A | 0006952 | biological_process | defense response |
| A | 0009694 | biological_process | jasmonic acid metabolic process |
| A | 0009696 | biological_process | salicylic acid metabolic process |
| A | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| A | 0016298 | molecular_function | lipase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0045087 | biological_process | innate immune response |
| A | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| A | 0080031 | molecular_function | methyl salicylate esterase activity |
| A | 0080032 | molecular_function | methyl jasmonate esterase activity |
| B | 0002376 | biological_process | immune system process |
| B | 0006952 | biological_process | defense response |
| B | 0009694 | biological_process | jasmonic acid metabolic process |
| B | 0009696 | biological_process | salicylic acid metabolic process |
| B | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| B | 0016298 | molecular_function | lipase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0045087 | biological_process | innate immune response |
| B | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| B | 0080031 | molecular_function | methyl salicylate esterase activity |
| B | 0080032 | molecular_function | methyl jasmonate esterase activity |
| C | 0002376 | biological_process | immune system process |
| C | 0006952 | biological_process | defense response |
| C | 0009694 | biological_process | jasmonic acid metabolic process |
| C | 0009696 | biological_process | salicylic acid metabolic process |
| C | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| C | 0016298 | molecular_function | lipase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0045087 | biological_process | innate immune response |
| C | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| C | 0080031 | molecular_function | methyl salicylate esterase activity |
| C | 0080032 | molecular_function | methyl jasmonate esterase activity |
| D | 0002376 | biological_process | immune system process |
| D | 0006952 | biological_process | defense response |
| D | 0009694 | biological_process | jasmonic acid metabolic process |
| D | 0009696 | biological_process | salicylic acid metabolic process |
| D | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| D | 0016298 | molecular_function | lipase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0045087 | biological_process | innate immune response |
| D | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| D | 0080031 | molecular_function | methyl salicylate esterase activity |
| D | 0080032 | molecular_function | methyl jasmonate esterase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE STH A 297 |
| Chain | Residue |
| A | GLY12 |
| A | GLY212 |
| A | HIS238 |
| A | ALA13 |
| A | SER81 |
| A | LEU82 |
| A | PHE107 |
| A | TYR122 |
| A | TRP131 |
| A | PHE151 |
| A | LEU181 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE STH B 298 |
| Chain | Residue |
| B | GLY12 |
| B | ALA13 |
| B | SER81 |
| B | LEU82 |
| B | PHE107 |
| B | TYR122 |
| B | TRP131 |
| B | LEU181 |
| B | GLY212 |
| B | HIS238 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE STH C 299 |
| Chain | Residue |
| C | GLY12 |
| C | ALA13 |
| C | SER81 |
| C | LEU82 |
| C | PHE107 |
| C | TYR122 |
| C | TRP131 |
| C | MSE149 |
| C | PHE151 |
| C | LEU181 |
| C | GLY212 |
| C | HIS238 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE STH D 300 |
| Chain | Residue |
| D | GLY12 |
| D | ALA13 |
| D | SER81 |
| D | LEU82 |
| D | PHE107 |
| D | TYR122 |
| D | PHE151 |
| D | LEU181 |
| D | GLY212 |
| D | HIS238 |
Functional Information from PROSITE/UniProt
| site_id | PS00120 |
| Number of Residues | 10 |
| Details | LIPASE_SER Lipases, serine active site. VILVGHSLGG |
| Chain | Residue | Details |
| A | VAL75-GLY84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17916738","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Y7I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c4x |
| Chain | Residue | Details |
| A | SER81 | |
| A | HIS238 | |
| A | ASP210 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c4x |
| Chain | Residue | Details |
| B | SER81 | |
| B | HIS238 | |
| B | ASP210 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c4x |
| Chain | Residue | Details |
| C | SER81 | |
| C | HIS238 | |
| C | ASP210 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c4x |
| Chain | Residue | Details |
| D | SER81 | |
| D | HIS238 | |
| D | ASP210 |
