1XET

Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0030639	biological_process	polyketide biosynthetic process
A	0050198	molecular_function	pinosylvin synthase activity
B	0005737	cellular_component	cytoplasm
B	0009058	biological_process	biosynthetic process
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0030639	biological_process	polyketide biosynthetic process
B	0050198	molecular_function	pinosylvin synthase activity
C	0005737	cellular_component	cytoplasm
C	0009058	biological_process	biosynthetic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0030639	biological_process	polyketide biosynthetic process
C	0050198	molecular_function	pinosylvin synthase activity
D	0005737	cellular_component	cytoplasm
D	0009058	biological_process	biosynthetic process
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0030639	biological_process	polyketide biosynthetic process
D	0050198	molecular_function	pinosylvin synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 3IO B 2000

Chain	Residue
B	CYS167
B	HOH2136
B	HOH2159
B	PHE218
B	ILE257
B	GLY258
B	PHE268
B	HIS306
B	ASN339
B	PHE376
B	HOH2062

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 3IO C 3000

Chain	Residue
C	CYS167
C	PHE218
C	ILE257
C	GLY258
C	HIS306
C	GLY308
C	ASN339
C	PHE376
C	HOH3155

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 3IO D 4000

Chain	Residue
D	THR135
D	CYS167
D	PHE218
D	ILE257
D	LEU266
D	PHE268
D	HIS306
D	ASN339
D	PHE376
D	MCA4001
D	HOH4195

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE MCA D 4001

Chain	Residue
D	LYS57
D	ARG60
D	ILE61
D	ARG64
D	LEU209
D	ASP210
D	VAL213
D	ILE257
D	LEU270
D	GLY308
D	GLY309
D	ARG310
D	ALA311
D	ILE312
D	3IO4000
D	HOH4158
D	HOH4171
D	HOH4173
D	HOH4174

---

Functional Information from PROSITE/UniProt

site_id	PS00441
Number of Residues	17
Details	CHALCONE_SYNTH Chalcone and stilbene synthases active site. RVgVfQhGCFAGGTvLR

Chain	Residue	Details
A	ARG159-ARG175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10023

Chain	Residue	Details
A	CYS167
B	CYS167
C	CYS167
D	CYS167

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	LYS57
D	LYS57
D	LEU270
D	GLY308
A	LEU270
A	GLY308
B	LYS57
B	LEU270
B	GLY308
C	LYS57
C	LEU270
C	GLY308

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
A	HIS306
A	ASN339
A	PHE218
A	CYS167

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
B	HIS306
B	ASN339
B	PHE218
B	CYS167

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
C	HIS306
C	ASN339
C	PHE218
C	CYS167

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
D	HIS306
D	ASN339
D	PHE218
D	CYS167

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