1WZU

Crystal structure of quinolinate synthase (nadA)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008987	molecular_function	quinolinate synthetase A activity
A	0009435	biological_process	NAD+ biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0019805	biological_process	quinolinate biosynthetic process
A	0034628	biological_process	'de novo' NAD+ biosynthetic process from L-aspartate
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MLT A 301

Chain	Residue
A	HIS21
A	HOH302
A	ASP37
A	SER38
A	TYR109
A	THR125
A	SER126
A	HIS196
A	SER212
A	THR213

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00568","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31390192","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15937336","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27224840","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27404889","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00568","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31390192","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15937336","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27404889","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00568","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27224840","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27404889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31390192","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KTT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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