1WYU

Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in holo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
A	0006546	biological_process	glycine catabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0019464	biological_process	glycine decarboxylation via glycine cleavage system
B	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
B	0005829	cellular_component	cytosol
B	0005960	cellular_component	glycine cleavage complex
B	0006546	biological_process	glycine catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016594	molecular_function	glycine binding
B	0019464	biological_process	glycine decarboxylation via glycine cleavage system
B	0030170	molecular_function	pyridoxal phosphate binding
B	0048046	cellular_component	apoplast
C	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
C	0006546	biological_process	glycine catabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0019464	biological_process	glycine decarboxylation via glycine cleavage system
D	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
D	0005829	cellular_component	cytosol
D	0005960	cellular_component	glycine cleavage complex
D	0006546	biological_process	glycine catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016594	molecular_function	glycine binding
D	0019464	biological_process	glycine decarboxylation via glycine cleavage system
D	0030170	molecular_function	pyridoxal phosphate binding
D	0048046	cellular_component	apoplast
E	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
E	0006546	biological_process	glycine catabolic process
E	0009116	biological_process	nucleoside metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0019464	biological_process	glycine decarboxylation via glycine cleavage system
F	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
F	0005829	cellular_component	cytosol
F	0005960	cellular_component	glycine cleavage complex
F	0006546	biological_process	glycine catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016594	molecular_function	glycine binding
F	0019464	biological_process	glycine decarboxylation via glycine cleavage system
F	0030170	molecular_function	pyridoxal phosphate binding
F	0048046	cellular_component	apoplast
G	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
G	0006546	biological_process	glycine catabolic process
G	0009116	biological_process	nucleoside metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0019464	biological_process	glycine decarboxylation via glycine cleavage system
H	0004375	molecular_function	glycine dehydrogenase (decarboxylating) activity
H	0005829	cellular_component	cytosol
H	0005960	cellular_component	glycine cleavage complex
H	0006546	biological_process	glycine catabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016594	molecular_function	glycine binding
H	0019464	biological_process	glycine decarboxylation via glycine cleavage system
H	0030170	molecular_function	pyridoxal phosphate binding
H	0048046	cellular_component	apoplast

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP B 475

Chain	Residue
A	THR320
B	SER168
B	ASP239
B	ALA241
B	ASN263
B	HIS265
B	LYS266
B	HOH631
A	THR321
A	HOH459
B	SER73
B	ALA131
B	GLY132
B	ALA133
B	GLU136
B	HIS166

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PLP D 475

Chain	Residue
C	THR320
C	THR321
C	HOH454
D	SER73
D	ALA131
D	GLY132
D	ALA133
D	GLU136
D	HIS166
D	SER168
D	ASP239
D	ALA241
D	ASN263
D	HIS265
D	LYS266

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP F 475

Chain	Residue
E	THR320
E	THR321
E	HOH440
F	SER73
F	ALA131
F	GLY132
F	ALA133
F	GLU136
F	HIS166
F	SER168
F	ASP239
F	ALA241
F	ASN263
F	HIS265
F	LYS266
F	HOH746

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site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP H 475

Chain	Residue
G	THR320
G	THR321
H	SER73
H	ALA131
H	GLY132
H	ALA133
H	GLU136
H	HIS166
H	SER168
H	ASP239
H	ALA241
H	ASN263
H	HIS265
H	LYS266
H	HOH482
H	HOH632

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Functional Information from PROSITE/UniProt

site_id	PS01036
Number of Residues	15
Details	HSP70_3 Heat shock hsp70 proteins family signature 3. LpLeGGrTPLPeVgE

Chain	Residue	Details
A	LEU181-GLU195

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_00713

Chain	Residue	Details
B	LYS266
D	LYS266
F	LYS266
H	LYS266

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