1WY7
crystal structure of a putative RNA methyltransferase PH1948 from Pyrococcus horikoshii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0032259 | biological_process | methylation |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SAH A 1001 |
| Chain | Residue |
| A | PHE18 |
| A | GLY59 |
| A | THR60 |
| A | GLY61 |
| A | VAL62 |
| A | GLU79 |
| A | VAL80 |
| A | ASP105 |
| A | VAL106 |
| A | ASN119 |
| A | PHE133 |
| A | LEU25 |
| A | HOH1013 |
| A | HOH1091 |
| A | GLU26 |
| A | GLN27 |
| A | TYR28 |
| A | ARG29 |
| A | THR30 |
| A | GLY57 |
| A | ALA58 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SAH B 1002 |
| Chain | Residue |
| B | PHE18 |
| B | LEU25 |
| B | GLU26 |
| B | GLN27 |
| B | TYR28 |
| B | ARG29 |
| B | THR30 |
| B | GLY57 |
| B | ALA58 |
| B | GLY59 |
| B | THR60 |
| B | VAL62 |
| B | LEU63 |
| B | GLU79 |
| B | VAL80 |
| B | ASP105 |
| B | VAL106 |
| B | ASN119 |
| B | PHE133 |
| B | HOH1013 |
| B | HOH1076 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE SAH C 1003 |
| Chain | Residue |
| C | PHE18 |
| C | LEU25 |
| C | GLU26 |
| C | GLN27 |
| C | TYR28 |
| C | THR30 |
| C | ASP55 |
| C | GLY57 |
| C | ALA58 |
| C | THR60 |
| C | GLU79 |
| C | VAL80 |
| C | ASP105 |
| C | VAL106 |
| C | ASN119 |
| C | PHE133 |
| C | HOH1018 |
| C | HOH1063 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH D 1004 |
| Chain | Residue |
| D | PHE18 |
| D | LEU25 |
| D | GLU26 |
| D | GLN27 |
| D | TYR28 |
| D | ARG29 |
| D | THR30 |
| D | GLY57 |
| D | ALA58 |
| D | THR60 |
| D | GLY61 |
| D | VAL62 |
| D | GLU79 |
| D | VAL80 |
| D | ASP105 |
| D | VAL106 |
| D | ASN119 |
| D | PHE133 |
| D | HOH1039 |
| D | HOH1057 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. VIMNPPF |
| Chain | Residue | Details |
| A | VAL116-PHE122 |
