1WE5

Crystal Structure of Alpha-Xylosidase from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
A	0042802	molecular_function	identical protein binding
A	0061634	molecular_function	alpha-D-xyloside xylohydrolase
A	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
B	0003824	molecular_function	catalytic activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0005975	biological_process	carbohydrate metabolic process
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
B	0042802	molecular_function	identical protein binding
B	0061634	molecular_function	alpha-D-xyloside xylohydrolase
B	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
C	0003824	molecular_function	catalytic activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0005975	biological_process	carbohydrate metabolic process
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030246	molecular_function	carbohydrate binding
C	0042802	molecular_function	identical protein binding
C	0061634	molecular_function	alpha-D-xyloside xylohydrolase
C	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
D	0003824	molecular_function	catalytic activity
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0005975	biological_process	carbohydrate metabolic process
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0030246	molecular_function	carbohydrate binding
D	0042802	molecular_function	identical protein binding
D	0061634	molecular_function	alpha-D-xyloside xylohydrolase
D	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
E	0003824	molecular_function	catalytic activity
E	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
E	0005975	biological_process	carbohydrate metabolic process
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0030246	molecular_function	carbohydrate binding
E	0042802	molecular_function	identical protein binding
E	0061634	molecular_function	alpha-D-xyloside xylohydrolase
E	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
F	0003824	molecular_function	catalytic activity
F	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
F	0005975	biological_process	carbohydrate metabolic process
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0030246	molecular_function	carbohydrate binding
F	0042802	molecular_function	identical protein binding
F	0061634	molecular_function	alpha-D-xyloside xylohydrolase
F	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MES A 801

Chain	Residue
A	PHE277
A	HIS304
A	ASP306
A	CYS307
A	TRP345
A	TRP380
A	LYS414
A	ASP416
A	ARG538

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MES B 802

Chain	Residue
B	THR274
B	HIS304
B	ASP306
B	TRP345
B	LYS414
B	ASP416
B	ARG538

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MES C 803

Chain	Residue
C	PHE277
C	HIS304
C	ASP306
C	TRP345
C	TRP380
C	LYS414
C	ASP416
C	ARG538

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MES D 804

Chain	Residue
D	THR274
D	HIS304
D	ASP306
D	TRP345
D	TRP380
D	LYS414
D	ASP416
D	PHE417
D	ARG538

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MES E 805

Chain	Residue
E	HIS304
E	ASP306
E	TRP345
E	TRP380
E	LYS414
E	ASP416
E	ARG538

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MES F 806

Chain	Residue
F	PHE277
F	HIS304
F	ASP306
F	CYS307
F	TRP345
F	TRP380
F	LYS414
F	ASP416
F	ARG538

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:15501829

Chain	Residue	Details
A	ASP416
B	ASP416
C	ASP416
D	ASP416
E	ASP416
F	ASP416

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:15501829

Chain	Residue	Details
A	GLU419
B	GLU419
C	GLU419
D	GLU419
E	GLU419
F	GLU419

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	ACT_SITE: Proton donor => ECO:0000269|PubMed:15501829

Chain	Residue	Details
A	ASP482
B	ASP482
C	ASP482
D	ASP482
E	ASP482
F	ASP482

---