Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0007596 | biological_process | blood coagulation |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0005509 | molecular_function | calcium ion binding |
B | 0006508 | biological_process | proteolysis |
B | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE L03 B 1248 |
Chain | Residue |
B | ASP189 |
B | PHE227 |
B | HOH2322 |
B | ALA190 |
B | GLU192 |
B | VAL213 |
B | TRP215 |
B | GLY216 |
B | GLY219 |
B | CYS220 |
B | GLY226 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE DMS B 1249 |
Chain | Residue |
B | ASN98 |
B | ILE174 |
B | TRP215 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE DMS B 1250 |
Chain | Residue |
B | LEU130 |
B | ILE162 |
B | ARG165 |
B | PHE181 |
B | HOH2323 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE DMS B 1251 |
Chain | Residue |
B | GLU127 |
B | SER129 |
B | SER171 |
B | PHE204 |
B | GLY223 |
B | LYS224 |
site_id | AC5 |
Number of Residues | 22 |
Details | BINDING SITE FOR CHAIN I OF HIRUGEN |
Chain | Residue |
B | PHE34 |
B | GLN38 |
B | LEU40 |
B | LEU65 |
B | ARG67 |
B | ARG73 |
B | THR74 |
B | ARG75 |
B | TYR76 |
B | LYS81 |
B | ILE82 |
B | MET84 |
B | GLN151 |
B | SER153 |
B | HOH2072 |
B | HOH2141 |
I | HOH2004 |
I | HOH2005 |
I | HOH2006 |
I | HOH2008 |
I | HOH2009 |
I | HOH2010 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
B | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
Chain | Residue | Details |
B | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
I | TYS63 | |
B | ASP102 | |
B | SER195 | |
Chain | Residue | Details |
B | ASN60 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | SER195 | |
B | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | SER195 | |
B | GLY193 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | GLY193 | |
B | HIS57 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 | |
B | GLY196 | |