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1WA8

Solution Structure of the CFP-10.ESAT-6 Complex. Major Virulence Determinants of Pathogenic Mycobacteria

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0009274cellular_componentpeptidoglycan-based cell wall
B0016020cellular_componentmembrane
B0020002cellular_componenthost cell plasma membrane
B0030430cellular_componenthost cell cytoplasm
B0042803molecular_functionprotein homodimerization activity
B0044165cellular_componenthost cell endoplasmic reticulum
B0044228cellular_componenthost cell surface
B0044315biological_processprotein secretion by the type VII secretion system
B0046812molecular_functionhost cell surface binding
B0052027biological_processsymbiont-mediated perturbation of host signal transduction pathway
B0052085biological_processsymbiont-mediated suppression of host T-cell mediated immune response
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues68
DetailsTRANSMEM: Helical => ECO:0000305|PubMed:25645924
ChainResidueDetails
BGLU612-GLY644
BALA650-THR686

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylthreonine; partial => ECO:0000269|PubMed:15378760, ECO:0007744|PubMed:21969609
ChainResidueDetails
BGLU603

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PDB entries from 2024-07-24

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