1W6T

Crystal Structure Of Octameric Enolase From Streptococcus pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0007155	biological_process	cell adhesion
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0042603	cellular_component	capsule
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0007155	biological_process	cell adhesion
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0042603	cellular_component	capsule
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 435

Chain	Residue
A	ASP242
A	GLU291
A	ASP318
A	HOH2195
A	HOH2204
A	HOH2212

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 435

Chain	Residue
B	HOH2172
B	HOH2173
B	HOH2174
B	ASP242
B	GLU291
B	ASP318

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 2PE A1434

Chain	Residue
A	GLU77
A	ALA78
A	ILE80

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 2PE B1434

Chain	Residue
B	GLU77
B	ALA78
B	ILE80
B	GLY81
B	TYR82
B	HOH2259

---

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKvNQIGTLTET

Chain	Residue	Details
A	ILE340-THR353

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	GLU205
B	GLU205

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	LYS343
B	LYS343

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	GLN163
B	LYS394
A	LYS343
A	ARG372
A	SER373
A	LYS394
B	GLN163
B	LYS343
B	ARG372
B	SER373

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00318, ECO:0000269|PubMed:15476816, ECO:0007744|PDB:1W6T

Chain	Residue	Details
A	ASP242
A	GLU291
A	ASP318
B	ASP242
B	GLU291
B	ASP318

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
A	GLU164
A	HIS371
A	LYS394
A	GLU205

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
B	GLU164
B	HIS371
B	LYS394
B	GLU205

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
A	GLU164
A	LYS343
A	HIS371
A	GLU205

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
B	GLU164
B	LYS343
B	HIS371
B	GLU205

---

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
A	HIS187
A	LYS343

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1els

Chain	Residue	Details
B	HIS187
B	LYS343

---