1W6T
Crystal Structure Of Octameric Enolase From Streptococcus pneumoniae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006096 | biological_process | glycolytic process |
| A | 0007155 | biological_process | cell adhesion |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0009986 | cellular_component | cell surface |
| A | 0016829 | molecular_function | lyase activity |
| A | 0042603 | cellular_component | capsule |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006096 | biological_process | glycolytic process |
| B | 0007155 | biological_process | cell adhesion |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0009986 | cellular_component | cell surface |
| B | 0016829 | molecular_function | lyase activity |
| B | 0042603 | cellular_component | capsule |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 435 |
| Chain | Residue |
| A | ASP242 |
| A | GLU291 |
| A | ASP318 |
| A | HOH2195 |
| A | HOH2204 |
| A | HOH2212 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 435 |
| Chain | Residue |
| B | HOH2172 |
| B | HOH2173 |
| B | HOH2174 |
| B | ASP242 |
| B | GLU291 |
| B | ASP318 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 2PE A1434 |
| Chain | Residue |
| A | GLU77 |
| A | ALA78 |
| A | ILE80 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2PE B1434 |
| Chain | Residue |
| B | GLU77 |
| B | ALA78 |
| B | ILE80 |
| B | GLY81 |
| B | TYR82 |
| B | HOH2259 |
Functional Information from PROSITE/UniProt
| site_id | PS00164 |
| Number of Residues | 14 |
| Details | ENOLASE Enolase signature. ILIKvNQIGTLTET |
| Chain | Residue | Details |
| A | ILE340-THR353 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15476816","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1W6T","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Region: {"description":"Antigenic epitope"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Motif: {"description":"Plasminogen-binding peptide","evidences":[{"source":"PubMed","id":"12828639","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| A | GLU164 | |
| A | HIS371 | |
| A | LYS394 | |
| A | GLU205 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| B | GLU164 | |
| B | HIS371 | |
| B | LYS394 | |
| B | GLU205 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| A | GLU164 | |
| A | LYS343 | |
| A | HIS371 | |
| A | GLU205 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| B | GLU164 | |
| B | LYS343 | |
| B | HIS371 | |
| B | GLU205 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| A | HIS187 | |
| A | LYS343 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1els |
| Chain | Residue | Details |
| B | HIS187 | |
| B | LYS343 |
