1W37
2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008674 | molecular_function | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity |
| A | 0008675 | molecular_function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity |
| A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| A | 0016829 | molecular_function | lyase activity |
| B | 0008674 | molecular_function | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity |
| B | 0008675 | molecular_function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity |
| B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| B | 0016829 | molecular_function | lyase activity |
| C | 0008674 | molecular_function | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity |
| C | 0008675 | molecular_function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity |
| C | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| C | 0016829 | molecular_function | lyase activity |
| D | 0008674 | molecular_function | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity |
| D | 0008675 | molecular_function | 2-dehydro-3-deoxy-phosphogluconate aldolase activity |
| D | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| D | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D1297 |
| Chain | Residue |
| D | PRO7 |
| D | GLY42 |
| D | THR43 |
| D | THR44 |
| D | TYR130 |
| D | LYS155 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A1295 |
| Chain | Residue |
| A | SER243 |
| A | HOH2187 |
| D | ARG106 |
| D | MET107 |
| D | SER108 |
| D | HIS111 |
| A | GLY240 |
| A | SER241 |
| A | LEU242 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B1295 |
| Chain | Residue |
| B | GLY240 |
| B | SER241 |
| B | LEU242 |
| B | SER243 |
| C | ARG106 |
| C | MET107 |
| C | SER108 |
| C | HIS111 |
| C | HOH2102 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B1296 |
| Chain | Residue |
| B | LYS86 |
| B | HOH2235 |
| B | HOH2236 |
| D | CYS120 |
| D | HIS125 |
| D | PRO126 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C1295 |
| Chain | Residue |
| A | LYS110 |
| C | ILE93 |
| C | HIS125 |
| C | PRO126 |
| C | HOH2097 |
| C | HOH2234 |
| C | HOH2236 |
| D | ASP268 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C1296 |
| Chain | Residue |
| C | CYS120 |
| C | PRO126 |
| C | CYS150 |
| C | HOH2116 |
| C | HOH2143 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C1297 |
| Chain | Residue |
| B | ARG106 |
| B | MET107 |
| B | SER108 |
| B | HIS111 |
| C | GLY240 |
| C | SER241 |
| C | LEU242 |
| C | SER243 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL D1295 |
| Chain | Residue |
| A | MET107 |
| A | SER108 |
| A | HIS111 |
| A | HOH2087 |
| D | PHE239 |
| D | GLY240 |
| D | SER241 |
| D | LEU242 |
| D | SER243 |
| D | HOH2203 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D1296 |
| Chain | Residue |
| D | LYS114 |
| D | THR118 |
| D | GLU121 |
| D | HOH2226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"PubMed","id":"15265860","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Proton shuttle","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1fdy |
| Chain | Residue | Details |
| A | LYS155 | |
| A | THR44 | |
| A | THR43 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1fdy |
| Chain | Residue | Details |
| B | LYS155 | |
| B | THR44 | |
| B | THR43 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1fdy |
| Chain | Residue | Details |
| C | LYS155 | |
| C | THR44 | |
| C | THR43 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1fdy |
| Chain | Residue | Details |
| D | LYS155 | |
| D | THR44 | |
| D | THR43 |
