1VZ7

Ornithine Acetyltransferase (ORF6 Gene Product - Clavulanic Acid Biosynthesis) from Streptomyces clavuligerus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004042	molecular_function	L-glutamate N-acetyltransferase activity
A	0004358	molecular_function	L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor
A	0005737	cellular_component	cytoplasm
A	0006526	biological_process	L-arginine biosynthetic process
A	0006592	biological_process	ornithine biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0033050	biological_process	clavulanic acid biosynthetic process
B	0004042	molecular_function	L-glutamate N-acetyltransferase activity
B	0004358	molecular_function	L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor
B	0005737	cellular_component	cytoplasm
B	0006526	biological_process	L-arginine biosynthetic process
B	0006592	biological_process	ornithine biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0033050	biological_process	clavulanic acid biosynthetic process
C	0004042	molecular_function	L-glutamate N-acetyltransferase activity
C	0004358	molecular_function	L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor
C	0005737	cellular_component	cytoplasm
C	0006526	biological_process	L-arginine biosynthetic process
C	0006592	biological_process	ornithine biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0033050	biological_process	clavulanic acid biosynthetic process
D	0004042	molecular_function	L-glutamate N-acetyltransferase activity
D	0004358	molecular_function	L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor
D	0005737	cellular_component	cytoplasm
D	0006526	biological_process	L-arginine biosynthetic process
D	0006592	biological_process	ornithine biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0033050	biological_process	clavulanic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A1391

Chain	Residue
A	THR111
A	GLY112
A	THR148
A	LYS170
A	THR181

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B1391

Chain	Residue
B	LYS170
B	MET174
B	THR181
B	THR111
B	GLY112
B	THR148
B	THR149

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C1391

Chain	Residue
C	THR111
C	GLY112
C	THR148
C	THR149
C	LYS170
C	THR181

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D1391

Chain	Residue
D	THR111
D	GLY112
D	THR148
D	THR149
D	LYS170
D	THR181

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Nucleophile"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21796301","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Site: {"description":"Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Site: {"description":"Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Site: {"description":"Cleavage; by autolysis"}

Chain

Residue

Details

---