1VYB
Endonuclease domain of human LINE1 ORF2p
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A1239 |
| Chain | Residue |
| A | HIS7 |
| A | ASN162 |
| A | LYS163 |
| A | LYS218 |
| A | ARG238 |
| A | HOH2215 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A1240 |
| Chain | Residue |
| A | ARG91 |
| A | HOH2216 |
| B | LYS85 |
| A | ILE62 |
| A | TYR63 |
| A | GLN64 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1241 |
| Chain | Residue |
| A | GLY17 |
| A | LEU18 |
| A | ASN19 |
| A | HIS45 |
| A | HOH2217 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO3 A1242 |
| Chain | Residue |
| A | LYS61 |
| A | TYR63 |
| A | PRO86 |
| A | HOH2218 |
| A | HOH2219 |
| B | TYR63 |
| B | PRO86 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1239 |
| Chain | Residue |
| A | LYS68 |
| A | LYS93 |
| B | ALA21 |
| B | ARG24 |
| B | HIS25 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B1240 |
| Chain | Residue |
| B | GLY17 |
| B | LEU18 |
| B | ASN19 |
| B | HIS45 |
| B | HOH2070 |
| B | HOH2220 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B1241 |
| Chain | Residue |
| A | GLN159 |
| B | HIS7 |
| B | LYS218 |
| B | ARG238 |
| B | HOH2221 |
| B | HOH2222 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B1242 |
| Chain | Residue |
| A | GLN159 |
| A | LYS218 |
| B | LYS218 |
| B | ARG219 |
| B | HOH2223 |
| B | HOH2224 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO3 B1243 |
| Chain | Residue |
| B | LYS71 |
| B | ALA72 |
| B | HIS96 |
| B | TYR115 |
| B | HOH2107 |
| B | HOH2225 |
| B | HOH2226 |
| B | HOH2227 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A1243 |
| Chain | Residue |
| A | THR224 |
| A | ASN225 |
| A | SER228 |
| A | HIS230 |
| A | SER231 |
| A | HOH2210 |
| A | HOH2220 |
| A | HOH2221 |
| B | TYR191 |
| B | TYR201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17626046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34554261","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ako |
| Chain | Residue | Details |
| A | ASP145 | |
| A | ASN14 | |
| A | ASN147 | |
| A | ASP205 | |
| A | HIS230 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ako |
| Chain | Residue | Details |
| B | ASP145 | |
| B | ASN14 | |
| B | ASN147 | |
| B | ASP205 | |
| B | HIS230 |
